Efficient porphyrin integrated UiO-66 probes for ratiometric fluorescence sensing of antibiotic residues in milk

• Published in: Mikrochimica acta (1966) Vol. 191; no. 6; p. 304
• Main Authors: Ma, Jinzhu, Shi, Yu-e, Song, Qian, Kou, Shufang, Wang, Zhenguang
• Format: Journal Article
• Language: English
• Published: Vienna Springer Vienna 01.06.2024; Springer Nature B.V
• Subjects: Amoxicillin; Amoxicillin - analysis; Amoxicillin - chemistry; Analytical Chemistry; Animals; Anti-Bacterial Agents - analysis; Anti-Bacterial Agents - chemistry; Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; Drug Residues - analysis; Energy transfer; Fluorescent Dyes - chemistry; Fluorescent indicators; Food Contamination - analysis; Hydrogen bonds; Limit of Detection; Metal-Organic Frameworks - chemistry; Microengineering; Milk - chemistry; Nanochemistry; Nanotechnology; Original Paper; Porphyrins; Porphyrins - chemistry; Spectrometry, Fluorescence - methods; Ratiometric fluorescence; UiO-66; Fluorometry; Amoxicillin; Metal − organic frameworks
• ISSN: 0026-3672; 1436-5073
• DOI: 10.1007/s00604-024-06391-4

Dual-emissive fluorescence probes were designed by integrating porphyrin into the frameworks of UiO-66 for ratiometric fluorescence sensing of amoxicillin (AMX). Porphyrin integrated UiO-66 showed dual emission in the blue and red region. AMX resulted in the quenching of blue fluorescence component, attributable to the charge neutralization and hydrogen bonds induced energy transfer. AMX was detected using (F 438 /F 654 ) as output signals. Two linear relationships were observed (from 10 to 1000 nM and 1 to 100 µM), with a limit of detection of 27 nM. The porphyrin integrated UiO-66 probe was used to detect AMX in practical samples. This work widens the road for the development of dual/multiple emissive fluorescence sensors for analytical applications, providing materials and theoretical supporting for food, environmental, and human safety. Graphical Abstract