The volume of the carotid bodies and blood pressure variability and pulse pressure in patients with essential hypertension

• Published in: Clinical radiology Vol. 71; no. 6; pp. 616.e7 - 616.e13
• Main Authors: Jaźwiec, P, Gać, P, Poręba, M, Sobieszczańska, M, Mazur, G, Poręba, R
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.06.2016
• Subjects: Aged; Blood Pressure; Carotid Body - diagnostic imaging; Carotid Body - pathology; Carotid Body - physiopathology; Computed Tomography Angiography - methods; Female; Humans; Hypertension - diagnostic imaging; Hypertension - physiopathology; Imaging, Three-Dimensional - methods; Male; Organ Size; Radiology; Reproducibility of Results; Sensitivity and Specificity
• ISSN: 0009-9260; 1365-229X
• DOI: 10.1016/j.crad.2016.02.022

Aim To assess the relationship between the volume of the carotid bodies (VrCB+lCB ) examined by means of computed tomography angiography (CTA) and blood pressure variability and pulse pressure (PP) in 24-hour ambulatory blood pressure monitoring (ABPM) in patients with essential hypertension. Materials and methods A group of 52 patients with essential hypertension was examined (mean age: 68.32±12.31 years), the sizes of carotid bodies were measured by means of carotid artery CTA, and 24-hour ABPM was carried out. The 24-hour ABPM established systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), PP, SBP variability (SBPV), and DBP variability (DBPV). Results SBP, MAP, and SBPV were significantly higher in the group of hypertension patients with VrCB+lCB equal to or above the median than in the group of hypertension patients with VrCB+lCB less than the median, as well as in the group of hypertension patients with oversized carotid bodies, than in the group of hypertension patients with normal VrCB+lCB . Moreover, the PP was statistically significantly higher in the group of hypertension patients with VrCB+lCB equal to or above the median than in the group of hypertension patients with VrCB+lCB less than the median. The existence of statistically significant positive linear relationships was revealed between VrCB+lCB and SBP, PP, and SBPV. A higher body mass index, older age, smoking, and higher VrCB+lCB are independent risk factors increasing SBPV in the research group. Conclusion A positive relationship between the size of the carotid bodies and variability of the SBP and PP is observed in patients with essential hypertension.