Primary Hyperparathyroidism in a 21 Year Old Patient of Turner Syndrome : A Rare Case Report

• Published in: Indian journal of otolaryngology, and head, and neck surgery Vol. 75; no. 2; pp. 1045 - 1048
• Main Authors: Rawat, Anshu, Grover, Mohnish, Mittal, Anugrah, Katara, Raksha, Samdhani, Sunil, Bhargava, Shruti, Mathur, Sandip, Sharma, Balram
• Format: Journal Article
• Language: English
• Published: New Delhi Springer India 01.06.2023; Springer Nature B.V
• Subjects: Case reports; Clinical Report; Endocrine disorders; Endocrine system; Head and Neck Surgery; Medicine; Medicine & Public Health; Otorhinolaryngology; Turner syndrome; Primary hyperparathyroidism
• ISSN: 2231-3796; 0973-7707
• DOI: 10.1007/s12070-022-03322-8

Turner syndrome is the most common chromosomal anomaly in females. The typical features include short stature, amenorrhoea, short webbed neck, shielded chest and many comorbidities like osteoporosis, cardiac anomalies, diabetes and hypothyroidism. Primary hyperparathyroidism caused by parathyroid adenoma is rarely reported in patients of turner syndrome. The exact cause is not known at present. We report a case of a 21 years old patient of Turner syndrome who had symptoms of renal stones and hypercalcemia. USG neck and sestamibi scans revealed left inferior parathyroid adenoma. Surgical excision of the involved gland was done which led to normalization of S. calcium and PTH levels. Although hyperparathyroidism is extremely rare in patients of Turner syndrome, any symptoms of renal stones, pathological fractures and hypercalcemia should raise the suspicion of parathyroid adenoma. Surgical management should be planned as early as possible.