Review on herbal medicine versus desmopressin therapy for pediatric monosymptomatic enuresis

• Published in: Advances in traditional medicine (Online) Vol. 22; no. 1; pp. 49 - 58
• Main Author: Jung, Hwan Su
• Format: Journal Article
• Language: English
• Published: Singapore Springer Singapore 01.03.2022; 융합한의과학연구소
• Subjects: Biomedical and Life Sciences; Biomedicine; Pharmacy; Review; 한의학; Herbal medicine; Nocturnal enuresis; Desmopressin; Monosymptomatic
• ISSN: 2662-4052; 2662-4060
• DOI: 10.1007/s13596-021-00622-2

This review compares the efficacy of herbal medicine and desmopressin therapy in managing pediatric monosymptomatic enuresis. Literature searches were performed on different databases without language restrictions or limitations on the publication year. The search date was August 3, 2021. All randomized control trials comparing herbal medicine and desmopressin therapy in managing children with monosymptomatic enuresis were included. Eight studies were included in the analysis. Overall, herbal medicine treatment was partially significant in terms of main outcomes, such as total effective rate and complete cure rate. In reducing the nighttime urine volume and urination frequency, herbal medicine treatment showed similar effects to desmopressin therapy. A significant improvement in the recurrence rate was observed in both herbal medicine treatment and combination treatment of herbal medicine with desmopressin compared to that of desmopressin monotherapy. In conclusion, herbal medicine treatment may complement or replace the shortcomings of desmopressin treatment in managing pediatric monosymptomatic enuresis.