Mucosa-Associated Lymphoid-Tissue Lymphoma

To the Editor: Diss et al. (July 15 issue) 1 described a case of mucosa-associated lymphoid-tissue (MALT) lymphoma presenting in multiple sites over a number of years. Using methods based on the polymerase chain reaction (PCR), they demonstrated a common clonal origin of cells from biopsy specimens...

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Bibliographic Details
Published inThe New England journal of medicine Vol. 329; no. 22; p. 1657
Main Author Zelenetz, A D
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 25.11.1993
Subjects
Gastric Mucosa - pathology
Humans
Lymphoid Tissue - pathology
Lymphoma, B-Cell - pathology
Polymerase Chain Reaction
Stomach Neoplasms - pathology
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Summary:To the Editor: Diss et al. (July 15 issue) 1 described a case of mucosa-associated lymphoid-tissue (MALT) lymphoma presenting in multiple sites over a number of years. Using methods based on the polymerase chain reaction (PCR), they demonstrated a common clonal origin of cells from biopsy specimens obtained over a 13-year period. One specimen was obtained during gastric resection and had histologic features of benign peptic ulcer (year 1), a lip-biopsy specimen had histologic features of Sjogren's syndrome (year 11), and gastric and bone marrow specimens revealed B-cell MALT lymphoma (year 13). The PCR amplification of the biopsy specimens demonstrated two . . .
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ObjectType-Commentary-2
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJM199311253292215