Efficient acetate sensor in biological media based on a selective Excited State Proton Transfer (ESPT) reaction

[Display omitted] •“On/off” fluorescent dye to detect acetate.•High sensitivity Acetate detection in biological serum is reported.•Acetate ions are relevant in physiological processes because it participates directly and/or indirectly in cancer metabolism. We have synthesized a new fluoride−containi...

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Published inSensors and actuators. B, Chemical Vol. 250; pp. 623 - 628
Main Authors Puente-Muñoz, Virginia, Paredes, Jose M., Resa, Sandra, Ortuño, Ana M., Talavera, Eva M., Miguel, Delia, Cuerva, Juan M., Crovetto, Luis
Format Journal Article
LanguageEnglish
Published Lausanne Elsevier B.V 01.10.2017
Elsevier Science Ltd
Subjects
Acetate sensor
Chemical synthesis
Excited state proton transfer (ESPT) reaction
Fatty acids
Fluorescence
Fluorescent probe
Hydrogen bonds
Metabolites
Protons
Acetate sensor
Fluorescent probe
Excited state proton transfer (ESPT) reaction
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Abstract [Display omitted] •“On/off” fluorescent dye to detect acetate.•High sensitivity Acetate detection in biological serum is reported.•Acetate ions are relevant in physiological processes because it participates directly and/or indirectly in cancer metabolism. We have synthesized a new fluoride−containing xanthenic dye able to dynamically and quantitatively detect acetate anion, a biologically relevant analyte, in water. We studied deeply the photophysical properties of the compound and verified its use as an acetate probe in synthetic serum.
AbstractList We have synthesized a new fluoride−containing xanthenic dye able to dynamically and quantitatively detect acetate anion, a biologically relevant analyte, in water. We studied deeply the photophysical properties of the compound and verified its use as an acetate probe in synthetic serum.
[Display omitted] •“On/off” fluorescent dye to detect acetate.•High sensitivity Acetate detection in biological serum is reported.•Acetate ions are relevant in physiological processes because it participates directly and/or indirectly in cancer metabolism. We have synthesized a new fluoride−containing xanthenic dye able to dynamically and quantitatively detect acetate anion, a biologically relevant analyte, in water. We studied deeply the photophysical properties of the compound and verified its use as an acetate probe in synthetic serum.
Author Cuerva, Juan M.
Paredes, Jose M.
Miguel, Delia
Puente-Muñoz, Virginia
Ortuño, Ana M.
Resa, Sandra
Crovetto, Luis
Talavera, Eva M.
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  givenname: Jose M.
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  fullname: Paredes, Jose M.
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  givenname: Sandra
  surname: Resa
  fullname: Resa, Sandra
  organization: Department of Organic Chemistry, Faculty of Sciences, University of Granada, C. U. Fuentenueva s/n, 18071 Granada, Spain
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  givenname: Ana M.
  surname: Ortuño
  fullname: Ortuño, Ana M.
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  givenname: Luis
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  organization: Department of Physical Chemistry, Faculty of Pharmacy, University of Granada, Cartuja Campus, 18071 Granada, Spain
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Cites_doi 10.1021/jp0402941
10.1038/cddis.2013.29
10.1021/jp044681m
10.1016/j.cell.2014.11.025
10.1039/C4OB00951G
10.1016/j.cell.2014.12.009
10.1021/jp405041c
10.1111/j.1751-1097.1994.tb05130.x
10.1016/j.talanta.2015.06.033
10.1021/jp0313019
10.1016/j.jlumin.2011.02.033
10.1186/s40170-016-0157-5
10.1002/chem.201502799
10.1016/S0969-8051(00)00195-5
10.1038/nmeth.2019
10.1074/jbc.M115.712166
10.1016/j.ccell.2014.12.002
10.1021/jp077249o
10.1016/j.cell.2014.11.020
10.1016/j.snb.2010.11.006
10.1039/b820742a
10.1021/ja043919h
10.1002/chem.201303113
10.1021/ol052655g
10.1039/b209598j
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Keywords Acetate sensor
Fluorescent probe
Excited state proton transfer (ESPT) reaction
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References Marques, Oliveira, Alves, Chaves, Coutinho, Corte-Real (bib0030) 2013; 4
Orte, Bermejo, Talavera, Crovetto, Alvarez-Pez (bib0100) 2005; 109
Suksai, Tuntulani (bib0040) 2003; 32
Lyssiotis, Cantley (bib0035) 2014; 159
Lakhter, Hamilton, Konger, Brustovetsky, Broxmeyer, Naidu (bib0020) 2016; 291
Martinez-Peragon, Miguel, Orte, Mota, Ruedas-Rama, Justicia (bib0095) 2014; 12
Paredes, Crovetto, Rios, Orte, Alvarez-Pez, Talavera (bib0070) 2009; 11
Martinez-Peragon, Miguel, Jurado, Justicia, Alvarez-Pez, Cuerva (bib0115) 2014; 20
Yguerabide, Talavera, Alvarez, Quintero (bib0120) 1994; 60
Crovetto, Paredes, Rios, Talavera, Alvarez-Pez (bib0125) 2007; 111
Schug, Peck, Jones, Zhang, Grosskurth, Alam (bib0005) 2015; 27
Tumanov, Bulusu, Gottlieb, Kamphorst (bib0060) 2016; 4
Jiang, Sun, Ren, Niu, Hu (bib0055) 2016; 146
Mahapatra, Hazra, Roy, Sahoo (bib0045) 2011; 131
Comerford, Huang, Du, Wang, Cai, Witkiewicz (bib0010) 2014; 159
Paredes, Giron, Ruedas-Rama, Orte, Crovetto, Talavera (bib0065) 2013; 117
Lakowicz (bib0075) 2006
Mashimo, Pichumani, Vemireddy, Hatanpaa, Singh, Sirasanagandla (bib0025) 2014; 159
Crovetto, Orte, Talavera, Alvarez-Pez, Cotlet, Thielemans (bib0130) 2004; 108
Huang, Lin, Lin (bib0050) 2011; 153
Boens, Basaric, Novikov, Crovetto, Orte, Talavera (bib0135) 2004; 108
Mottram, Boonyarattanakalin, Kovel, Peterson (bib0085) 2006; 8
Urano, Kamiya, Kanda, Ueno, Hirose, Nagano (bib0090) 2005; 127
O'Connor, Phillips (bib0105) 1984
Yoshimoto, Waki, Yonekura, Sadato, Murata, Omata (bib0015) 2001; 28
Schindelin, Arganda-Carreras, Frise, Kaynig, Longair, Pietzsch (bib0110) 2012; 9
Resa, Orte, Miguel, Paredes, Puente-Munoz, Salto (bib0080) 2015; 21
O'Connor (10.1016/j.snb.2017.04.191_bib0105) 1984
Paredes (10.1016/j.snb.2017.04.191_bib0065) 2013; 117
Mahapatra (10.1016/j.snb.2017.04.191_bib0045) 2011; 131
Yguerabide (10.1016/j.snb.2017.04.191_bib0120) 1994; 60
Mottram (10.1016/j.snb.2017.04.191_bib0085) 2006; 8
Schug (10.1016/j.snb.2017.04.191_bib0005) 2015; 27
Schindelin (10.1016/j.snb.2017.04.191_bib0110) 2012; 9
Martinez-Peragon (10.1016/j.snb.2017.04.191_bib0115) 2014; 20
Resa (10.1016/j.snb.2017.04.191_bib0080) 2015; 21
Crovetto (10.1016/j.snb.2017.04.191_bib0125) 2007; 111
Lyssiotis (10.1016/j.snb.2017.04.191_bib0035) 2014; 159
Jiang (10.1016/j.snb.2017.04.191_bib0055) 2016; 146
Paredes (10.1016/j.snb.2017.04.191_bib0070) 2009; 11
Huang (10.1016/j.snb.2017.04.191_bib0050) 2011; 153
Orte (10.1016/j.snb.2017.04.191_bib0100) 2005; 109
Tumanov (10.1016/j.snb.2017.04.191_bib0060) 2016; 4
Suksai (10.1016/j.snb.2017.04.191_bib0040) 2003; 32
Lakhter (10.1016/j.snb.2017.04.191_bib0020) 2016; 291
Mashimo (10.1016/j.snb.2017.04.191_bib0025) 2014; 159
Comerford (10.1016/j.snb.2017.04.191_bib0010) 2014; 159
Crovetto (10.1016/j.snb.2017.04.191_bib0130) 2004; 108
Lakowicz (10.1016/j.snb.2017.04.191_bib0075) 2006
Urano (10.1016/j.snb.2017.04.191_bib0090) 2005; 127
Marques (10.1016/j.snb.2017.04.191_bib0030) 2013; 4
Boens (10.1016/j.snb.2017.04.191_bib0135) 2004; 108
Martinez-Peragon (10.1016/j.snb.2017.04.191_bib0095) 2014; 12
Yoshimoto (10.1016/j.snb.2017.04.191_bib0015) 2001; 28
References_xml – volume: 117
  start-page: 8143
  year: 2013
  end-page: 8149
  ident: bib0065
  article-title: Real-time phosphate sensing in living cells using fluorescence lifetime imaging microscopy (FLIM)
  publication-title: J. Phys. Chem. B
  contributor:
    fullname: Talavera
– year: 2006
  ident: bib0075
  article-title: Principles of Fluorescence Spectroscopy
  contributor:
    fullname: Lakowicz
– volume: 108
  start-page: 8180
  year: 2004
  end-page: 8189
  ident: bib0135
  article-title: Identifiability of the model of the intermolecular excited-state proton exchange reaction in the presence of pH buffer
  publication-title: J. Phys. Chem. A
  contributor:
    fullname: Talavera
– volume: 159
  start-page: 1591
  year: 2014
  end-page: 1602
  ident: bib0010
  article-title: Acetate dependence of tumors
  publication-title: Cell
  contributor:
    fullname: Witkiewicz
– volume: 111
  start-page: 13311
  year: 2007
  end-page: 13320
  ident: bib0125
  article-title: Photophysics of a xanthenic derivative dye useful as an ‘on/off' fluorescence probe
  publication-title: J. Phys. Chem. A
  contributor:
    fullname: Alvarez-Pez
– volume: 60
  start-page: 435
  year: 1994
  end-page: 441
  ident: bib0120
  article-title: Steady-state fluorescence method for evaluating excited-state proton reactions − application to fluorescein
  publication-title: Photochem. Photobiol.
  contributor:
    fullname: Quintero
– volume: 159
  start-page: 1603
  year: 2014
  end-page: 1614
  ident: bib0025
  article-title: Acetate is a bioenergetic substrate for human glioblastoma and brain metastases
  publication-title: Cell
  contributor:
    fullname: Sirasanagandla
– volume: 4
  year: 2013
  ident: bib0030
  article-title: Acetate-induced apoptosis in colorectal carcinoma cells involves lysosomal membrane permeabilization and cathepsin D release
  publication-title: Cell Death Dis.
  contributor:
    fullname: Corte-Real
– volume: 12
  start-page: 6432
  year: 2014
  end-page: 6439
  ident: bib0095
  article-title: Rational design of a new fluorescent ‘ON/OFF' xanthene dye for phosphate detection in live cells
  publication-title: Org. Biomol. Chem.
  contributor:
    fullname: Justicia
– volume: 27
  start-page: 57
  year: 2015
  end-page: 71
  ident: bib0005
  article-title: Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress
  publication-title: Cancer Cell
  contributor:
    fullname: Alam
– volume: 108
  start-page: 6082
  year: 2004
  end-page: 6092
  ident: bib0130
  article-title: Global compartmental analysis of the excited-state reaction between fluorescein and (+-)-N-acetyl aspartic acid
  publication-title: J. Phys. Chem. B
  contributor:
    fullname: Thielemans
– volume: 28
  start-page: 117
  year: 2001
  end-page: 122
  ident: bib0015
  article-title: Characterization of acetate metabolism in tumor cells in relation to cell proliferation: acetate metabolism in tumor cells
  publication-title: Nucl. Med. Biol.
  contributor:
    fullname: Omata
– volume: 32
  start-page: 192
  year: 2003
  end-page: 202
  ident: bib0040
  article-title: Chromogenic anion sensors
  publication-title: Chem. Soc. Rev.
  contributor:
    fullname: Tuntulani
– volume: 4
  year: 2016
  ident: bib0060
  article-title: A rapid method for quantifying free and bound acetate based on alkylation and GC–MS analysis
  publication-title: Cancer Metab.
  contributor:
    fullname: Kamphorst
– volume: 9
  start-page: 676
  year: 2012
  end-page: 682
  ident: bib0110
  article-title: Fiji: an open-source platform for biological-image analysis
  publication-title: Nat. Methods
  contributor:
    fullname: Pietzsch
– volume: 291
  start-page: 21869
  year: 2016
  end-page: 21879
  ident: bib0020
  article-title: Glucose-independent acetate metabolism promotes melanoma cell survival and tumor growth
  publication-title: J. Biol. Chem.
  contributor:
    fullname: Naidu
– volume: 131
  start-page: 1255
  year: 2011
  end-page: 1259
  ident: bib0045
  article-title: A simple coumarin-based colorimetric and ratiometric chemosensor for acetate and a selective fluorescence turn-on probe for iodide
  publication-title: J. Lumin.
  contributor:
    fullname: Sahoo
– volume: 21
  start-page: 14772
  year: 2015
  end-page: 14779
  ident: bib0080
  article-title: New dual fluorescent probe for simultaneous biothiol and phosphate bioimaging
  publication-title: Chem.-A Eur. J.
  contributor:
    fullname: Salto
– volume: 8
  start-page: 581
  year: 2006
  end-page: 584
  ident: bib0085
  article-title: The Pennsylvania green fluorophore: a hybrid of Oregon green and Tokyo green for the construction of hydrophobic and pH-insensitive molecular probes
  publication-title: Organic Lett.
  contributor:
    fullname: Peterson
– volume: 159
  start-page: 1492
  year: 2014
  end-page: 1494
  ident: bib0035
  article-title: Acetate fuels the cancer engine
  publication-title: Cell
  contributor:
    fullname: Cantley
– volume: 109
  start-page: 2840
  year: 2005
  end-page: 2846
  ident: bib0100
  article-title: 2', 7'-difluorofluorescein excited-state proton reactions: correlation between time-resolved emission and steady-state fluorescence intensity
  publication-title: J. Phys. Chem. A
  contributor:
    fullname: Alvarez-Pez
– volume: 20
  start-page: 447
  year: 2014
  end-page: 455
  ident: bib0115
  article-title: Synthesis and photophysics of a new family of fluorescent 9-alkyl-substituted xanthenones
  publication-title: Chemistry
  contributor:
    fullname: Cuerva
– volume: 11
  start-page: 5400
  year: 2009
  end-page: 5407
  ident: bib0070
  article-title: Tuned lifetime, at the ensemble and single molecule level, of a xanthenic fluorescent dye by means of a buffer-mediated excited-state proton exchange reaction
  publication-title: Phys. Chem. Chem. Phys.
  contributor:
    fullname: Talavera
– year: 1984
  ident: bib0105
  article-title: Time-correlated Single Photon Counting
  contributor:
    fullname: Phillips
– volume: 153
  start-page: 404
  year: 2011
  end-page: 408
  ident: bib0050
  article-title: Fluorescent acetate-sensing in aqueous solution
  publication-title: Sens. Actuators B-Chem.
  contributor:
    fullname: Lin
– volume: 146
  start-page: 732
  year: 2016
  end-page: 736
  ident: bib0055
  article-title: A novel colorimetric and fluorescent iminocoumarin-based chemosensor for acetate ion and its application to living cell imaging
  publication-title: Talanta
  contributor:
    fullname: Hu
– volume: 127
  start-page: 4888
  year: 2005
  end-page: 4894
  ident: bib0090
  article-title: Evolution of fluorescein as a platform for finely tunable fluorescence probes
  publication-title: J. Am. Chem. Soc.
  contributor:
    fullname: Nagano
– volume: 108
  start-page: 8180
  year: 2004
  ident: 10.1016/j.snb.2017.04.191_bib0135
  article-title: Identifiability of the model of the intermolecular excited-state proton exchange reaction in the presence of pH buffer
  publication-title: J. Phys. Chem. A
  doi: 10.1021/jp0402941
  contributor:
    fullname: Boens
– volume: 4
  year: 2013
  ident: 10.1016/j.snb.2017.04.191_bib0030
  article-title: Acetate-induced apoptosis in colorectal carcinoma cells involves lysosomal membrane permeabilization and cathepsin D release
  publication-title: Cell Death Dis.
  doi: 10.1038/cddis.2013.29
  contributor:
    fullname: Marques
– volume: 109
  start-page: 2840
  year: 2005
  ident: 10.1016/j.snb.2017.04.191_bib0100
  article-title: 2', 7'-difluorofluorescein excited-state proton reactions: correlation between time-resolved emission and steady-state fluorescence intensity
  publication-title: J. Phys. Chem. A
  doi: 10.1021/jp044681m
  contributor:
    fullname: Orte
– volume: 159
  start-page: 1603
  year: 2014
  ident: 10.1016/j.snb.2017.04.191_bib0025
  article-title: Acetate is a bioenergetic substrate for human glioblastoma and brain metastases
  publication-title: Cell
  doi: 10.1016/j.cell.2014.11.025
  contributor:
    fullname: Mashimo
– volume: 12
  start-page: 6432
  year: 2014
  ident: 10.1016/j.snb.2017.04.191_bib0095
  article-title: Rational design of a new fluorescent ‘ON/OFF' xanthene dye for phosphate detection in live cells
  publication-title: Org. Biomol. Chem.
  doi: 10.1039/C4OB00951G
  contributor:
    fullname: Martinez-Peragon
– volume: 159
  start-page: 1492
  year: 2014
  ident: 10.1016/j.snb.2017.04.191_bib0035
  article-title: Acetate fuels the cancer engine
  publication-title: Cell
  doi: 10.1016/j.cell.2014.12.009
  contributor:
    fullname: Lyssiotis
– volume: 117
  start-page: 8143
  year: 2013
  ident: 10.1016/j.snb.2017.04.191_bib0065
  article-title: Real-time phosphate sensing in living cells using fluorescence lifetime imaging microscopy (FLIM)
  publication-title: J. Phys. Chem. B
  doi: 10.1021/jp405041c
  contributor:
    fullname: Paredes
– volume: 60
  start-page: 435
  year: 1994
  ident: 10.1016/j.snb.2017.04.191_bib0120
  article-title: Steady-state fluorescence method for evaluating excited-state proton reactions − application to fluorescein
  publication-title: Photochem. Photobiol.
  doi: 10.1111/j.1751-1097.1994.tb05130.x
  contributor:
    fullname: Yguerabide
– volume: 146
  start-page: 732
  year: 2016
  ident: 10.1016/j.snb.2017.04.191_bib0055
  article-title: A novel colorimetric and fluorescent iminocoumarin-based chemosensor for acetate ion and its application to living cell imaging
  publication-title: Talanta
  doi: 10.1016/j.talanta.2015.06.033
  contributor:
    fullname: Jiang
– year: 2006
  ident: 10.1016/j.snb.2017.04.191_bib0075
  contributor:
    fullname: Lakowicz
– volume: 108
  start-page: 6082
  year: 2004
  ident: 10.1016/j.snb.2017.04.191_bib0130
  article-title: Global compartmental analysis of the excited-state reaction between fluorescein and (+-)-N-acetyl aspartic acid
  publication-title: J. Phys. Chem. B
  doi: 10.1021/jp0313019
  contributor:
    fullname: Crovetto
– volume: 131
  start-page: 1255
  year: 2011
  ident: 10.1016/j.snb.2017.04.191_bib0045
  article-title: A simple coumarin-based colorimetric and ratiometric chemosensor for acetate and a selective fluorescence turn-on probe for iodide
  publication-title: J. Lumin.
  doi: 10.1016/j.jlumin.2011.02.033
  contributor:
    fullname: Mahapatra
– volume: 4
  year: 2016
  ident: 10.1016/j.snb.2017.04.191_bib0060
  article-title: A rapid method for quantifying free and bound acetate based on alkylation and GC–MS analysis
  publication-title: Cancer Metab.
  doi: 10.1186/s40170-016-0157-5
  contributor:
    fullname: Tumanov
– volume: 21
  start-page: 14772
  year: 2015
  ident: 10.1016/j.snb.2017.04.191_bib0080
  article-title: New dual fluorescent probe for simultaneous biothiol and phosphate bioimaging
  publication-title: Chem.-A Eur. J.
  doi: 10.1002/chem.201502799
  contributor:
    fullname: Resa
– volume: 28
  start-page: 117
  year: 2001
  ident: 10.1016/j.snb.2017.04.191_bib0015
  article-title: Characterization of acetate metabolism in tumor cells in relation to cell proliferation: acetate metabolism in tumor cells
  publication-title: Nucl. Med. Biol.
  doi: 10.1016/S0969-8051(00)00195-5
  contributor:
    fullname: Yoshimoto
– volume: 9
  start-page: 676
  year: 2012
  ident: 10.1016/j.snb.2017.04.191_bib0110
  article-title: Fiji: an open-source platform for biological-image analysis
  publication-title: Nat. Methods
  doi: 10.1038/nmeth.2019
  contributor:
    fullname: Schindelin
– volume: 291
  start-page: 21869
  year: 2016
  ident: 10.1016/j.snb.2017.04.191_bib0020
  article-title: Glucose-independent acetate metabolism promotes melanoma cell survival and tumor growth
  publication-title: J. Biol. Chem.
  doi: 10.1074/jbc.M115.712166
  contributor:
    fullname: Lakhter
– volume: 27
  start-page: 57
  year: 2015
  ident: 10.1016/j.snb.2017.04.191_bib0005
  article-title: Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress
  publication-title: Cancer Cell
  doi: 10.1016/j.ccell.2014.12.002
  contributor:
    fullname: Schug
– volume: 111
  start-page: 13311
  year: 2007
  ident: 10.1016/j.snb.2017.04.191_bib0125
  article-title: Photophysics of a xanthenic derivative dye useful as an ‘on/off' fluorescence probe
  publication-title: J. Phys. Chem. A
  doi: 10.1021/jp077249o
  contributor:
    fullname: Crovetto
– volume: 159
  start-page: 1591
  year: 2014
  ident: 10.1016/j.snb.2017.04.191_bib0010
  article-title: Acetate dependence of tumors
  publication-title: Cell
  doi: 10.1016/j.cell.2014.11.020
  contributor:
    fullname: Comerford
– volume: 153
  start-page: 404
  year: 2011
  ident: 10.1016/j.snb.2017.04.191_bib0050
  article-title: Fluorescent acetate-sensing in aqueous solution
  publication-title: Sens. Actuators B-Chem.
  doi: 10.1016/j.snb.2010.11.006
  contributor:
    fullname: Huang
– volume: 11
  start-page: 5400
  year: 2009
  ident: 10.1016/j.snb.2017.04.191_bib0070
  article-title: Tuned lifetime, at the ensemble and single molecule level, of a xanthenic fluorescent dye by means of a buffer-mediated excited-state proton exchange reaction
  publication-title: Phys. Chem. Chem. Phys.
  doi: 10.1039/b820742a
  contributor:
    fullname: Paredes
– volume: 127
  start-page: 4888
  year: 2005
  ident: 10.1016/j.snb.2017.04.191_bib0090
  article-title: Evolution of fluorescein as a platform for finely tunable fluorescence probes
  publication-title: J. Am. Chem. Soc.
  doi: 10.1021/ja043919h
  contributor:
    fullname: Urano
– volume: 20
  start-page: 447
  year: 2014
  ident: 10.1016/j.snb.2017.04.191_bib0115
  article-title: Synthesis and photophysics of a new family of fluorescent 9-alkyl-substituted xanthenones
  publication-title: Chemistry
  doi: 10.1002/chem.201303113
  contributor:
    fullname: Martinez-Peragon
– volume: 8
  start-page: 581
  year: 2006
  ident: 10.1016/j.snb.2017.04.191_bib0085
  article-title: The Pennsylvania green fluorophore: a hybrid of Oregon green and Tokyo green for the construction of hydrophobic and pH-insensitive molecular probes
  publication-title: Organic Lett.
  doi: 10.1021/ol052655g
  contributor:
    fullname: Mottram
– year: 1984
  ident: 10.1016/j.snb.2017.04.191_bib0105
  contributor:
    fullname: O'Connor
– volume: 32
  start-page: 192
  year: 2003
  ident: 10.1016/j.snb.2017.04.191_bib0040
  article-title: Chromogenic anion sensors
  publication-title: Chem. Soc. Rev.
  doi: 10.1039/b209598j
  contributor:
    fullname: Suksai
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Snippet [Display omitted] •“On/off” fluorescent dye to detect acetate.•High sensitivity Acetate detection in biological serum is reported.•Acetate ions are relevant in...
We have synthesized a new fluoride−containing xanthenic dye able to dynamically and quantitatively detect acetate anion, a biologically relevant analyte, in...
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StartPage 623
SubjectTerms Acetate sensor
Chemical synthesis
Excited state proton transfer (ESPT) reaction
Fatty acids
Fluorescence
Fluorescent probe
Hydrogen bonds
Metabolites
Protons
Title Efficient acetate sensor in biological media based on a selective Excited State Proton Transfer (ESPT) reaction
URI https://dx.doi.org/10.1016/j.snb.2017.04.191
https://www.proquest.com/docview/2089732596
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