Iron-catalysed fluoroaromatic coupling reactions under catalytic modulation with 1,2-bis(diphenylphosphino)benzene

A catalytic amount of 1,2-bis(diphenylphosphino) benzene (DPPBz) achieves selective cleavage of sp(3)-carbon-halogen bond in the iron-catalysed cross-coupling between polyfluorinated arylzinc reagents and alkyl halides, which was unachievable with a stoichiometric modifier such as TMEDA; the selecti...

Full description

Saved in:
Bibliographic Details
Published inChemical communications (Cambridge, England) no. 10; pp. 1216 - 1218
Main Authors Hatakeyama, Takuji, Kondo, Yoshiyuki, Fujiwara, Yu-ichi, Takaya, Hikaru, Ito, Shingo, Nakamura, Eiichi, Nakamura, Masaharu
Format Journal Article
LanguageEnglish
Published CAMBRIDGE Royal Soc Chemistry 01.01.2009
Subjects
Benzene Derivatives - chemistry
Catalysis
Chemistry
Chemistry, Multidisciplinary
Iron - chemistry
Molecular Structure
Organophosphonates - chemistry
Physical Sciences
Science & Technology
Spectrophotometry
CHLORIDES
CROSS-COUPLINGS
SECONDARY ALKYL-HALIDES
GRIGNARD-REAGENTS
LIQUID-CRYSTALS
ARYLATION
Online AccessGet full text

Cover

More Information
Summary:A catalytic amount of 1,2-bis(diphenylphosphino) benzene (DPPBz) achieves selective cleavage of sp(3)-carbon-halogen bond in the iron-catalysed cross-coupling between polyfluorinated arylzinc reagents and alkyl halides, which was unachievable with a stoichiometric modifier such as TMEDA; the selective iron-catalysed fluoroaromatic coupling provides easy and practical access to poly-fluorinated aromatic compounds.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1359-7345
1364-548X
DOI:10.1039/b820879d