Use of Ultrasound Contrast Agents in Relation to Percutaneous Interventional Procedures: A Systematic Review and Pictorial Essay

• Published in: Journal of ultrasound in medicine Vol. 37; no. 6; pp. 1305 - 1324
• Main Authors: Nolsøe, Christian Pállson, Nolsøe, Alexander Bjørneboe, Klubien, Jeanett, Pommergaard, Hans‐Christian, Rosenberg, Jacob, Meloni, Maria Franca, Lorentzen, Torben
• Format: Journal Article
• Language: English
• Published: England 01.06.2018
• Subjects: contrast agents (clinical); Contrast Media; contrast‐enhanced ultrasound; contrast‐enhanced ultrasound‐guided intervention; Humans; Image Enhancement - methods; interventional ultrasound; invasive techniques; tumor ablation; Ultrasonography, Interventional; ultrasound‐guided ablation; ultrasound‐guided biopsy; contrast-enhanced ultrasound; tumor ablation; contrast-enhanced ultrasound-guided intervention; interventional ultrasound; ultrasound-guided biopsy; ultrasound-guided ablation; contrast agents (clinical); invasive techniques
• ISSN: 0278-4297; 1550-9613
• DOI: 10.1002/jum.14498

The aim of this article is to provide an inventory of the use of contrast‐enhanced ultrasound (CEUS) in relation to percutaneous interventional procedures. The article is structured into a systematic literature review followed by a clinical part relating to percutaneous CEUS‐guided procedures. A literature search identified 3109 records. After screening, 55 articles were analyzed and supplemented with pictorial material to explain the techniques. In conclusion, the best‐evidenced indications for CEUS‐guided interventions are biopsy and ablation of inconspicuous or B‐mode–invisible tumors, intraprocedural ablation control and follow‐up, as well as percutaneous transhepatic cholangiography and drainage procedures.