Menopausal hormonal therapy in gynaecological cancers: An evidence‐based approach for clinical management
Treatment for gynaecological malignancies often requires oophorectomy or loss of ovarian function from adjuvant treatment. Premature or early menopause caused by gynaecological cancer treatment may require menopausal hormonal therapy (MHT) to treat vasomotor symptoms. However, concerns exist due to...
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Published in | Australian & New Zealand journal of obstetrics & gynaecology Vol. 60; no. 6; pp. 942 - 945 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Australia
01.12.2020
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Subjects | |
Online Access | Get full text |
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Summary: | Treatment for gynaecological malignancies often requires oophorectomy or loss of ovarian function from adjuvant treatment. Premature or early menopause caused by gynaecological cancer treatment may require menopausal hormonal therapy (MHT) to treat vasomotor symptoms. However, concerns exist due to theoretical risks of stimulation of hormonal‐sensitive tumours and hence increasing recurrence risk. There are small numbers of often underpowered fair to poor quality studies indicating that MHT is safe with most gynaecological malignancies. These studies are of variable quality with most being retrospective. We present the available data on this subject relative to the common types of gynaecological cancer. |
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Bibliography: | The authors report no conflict of interest. Conflicts of Interest |
ISSN: | 0004-8666 1479-828X |
DOI: | 10.1111/ajo.13237 |