A Preliminary Study on Quantitative Quality Measurements of the Urethral Rhabdosphincter Muscle by Supersonic Shear Wave Imaging in Women With Stress Urinary Incontinence

• Published in: Journal of ultrasound in medicine Vol. 39; no. 8; pp. 1615 - 1621
• Main Authors: Zhao, Baihua, Wen, Lieming, Chen, Wenjie, Qing, Zhenzhen, Liu, Dan, Liu, Minghui
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.08.2020
• Subjects: Elasticity Imaging Techniques; Female; Humans; Muscles; Prospective Studies; stress urinary incontinence; supersonic shear wave imaging; ultrasound quantitation imaging; Urethra - diagnostic imaging; urethral quality; urethral rhabdosphincter muscle; Urinary Incontinence, Stress - diagnostic imaging; ultrasound quantitation imaging; supersonic shear wave imaging; urethral quality; stress urinary incontinence; urethral rhabdosphincter muscle
• ISSN: 0278-4297; 1550-9613; 1550-9613
• DOI: 10.1002/jum.15255

Objectives To quantitatively assess the quality of the urethral rhabdosphincter muscle by measuring its shear wave velocity (Vs) and calculating the Young modulus (E) with supersonic shear wave imaging (SSI). Methods This was a prospective study of 43 women with SUI and 52 female control participants who underwent a transperineal US examination with SSI. Supersonic shear wave imaging was performed at rest with a linear transducer and a specialized‐preset procedure. The stability and validity of the shear waves were automatically assessed by the SSI procedure. The SSI images were visualized in a color‐coded elastographic image. In the postprocessing analysis, the ventral part of the urethral rhabdosphincter muscle was manually outlined. The mean Vs and the mean E of the muscle were measured by the SSI procedure. The relationship between the mean Vs, mean E, and SUI was evaluated. Results The SSI examination was successfully performed in 40 patients with SUI (93.0%) and 40 female control participants (76.9%). No significant differences between the groups in age, body mass index, and parity were identified. For the SUI and control groups, the mean Vs values were 2.54 and 2.73 m/s, respectively, and the mean E values were was 19.7 and 22.7kPa. Significant correlations were found between SUI and the mean Vs as well as the mean E (Spearman correlation coefficients, –0.41 and –0.43; P < .05). Conclusions The mechanical properties of the urethral sphincter can be quantitatively assessed by SSI. The stiffness of the urethral rhabdosphincter muscle was significantly lower in women with SUI.