Regioselectively N-Functionalised 14-Membered Azapyridinomacrocycles Bearing Trialkanoic Acid Side Chains as Ligands for Lanthanide Ions

• Published in: European journal of organic chemistry Vol. 2004; no. 21; pp. 4424 - 4436
• Main Authors: Dioury, Fabienne, Sylvestre, Isabelle, Siaugue, Jean-Michel, Wintgens, Véronique, Ferroud, Clotilde, Favre-Réguillon, Alain, Foos, Jacques, Guy, Alain
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 01.11.2004; WILEY‐VCH Verlag; Wiley
• Subjects: Chemistry; Chemistry, Organic; Lanthanides; Luminescence; Macrocyclic ligands; N,O ligands; O ligands; Physical Sciences; Science & Technology; UV/Vis spectroscopy; ARM MACROCYCLIC LIGANDS; TRIACETATE LIGAND; CRYSTAL-STRUCTURE; PYRIDINE; STABILITY-CONSTANTS; UV/Vis spectroscopy; lanthanides; N,O ligands; ZINC(II) COMPLEXES; luminescence; macrocyclic ligands; CONTAINING TETRA-AZA; PENDANT-ARM; MRI CONTRAST AGENTS
• ISSN: 1434-193X; 1099-0690
• DOI: 10.1002/ejoc.200400264

Four 14‐membered azamacrocycles 2a−d, each containing a pyridine moiety and three acetic and/or propionic acid pendent arms, were prepared from regioselectively functionalised polyamines. The stability constants of the lanthanide complexes (La, Pr, Nd, Eu, Gd, Tb, Er, Yb, Lu) formed with the triacetic acid compound 2a were determined by spectroscopic methods (luminescence and/or UV/Vis spectroscopy). Other characteristics of the luminescent EuIII and TbIII complexes formed with the triacetic acid derivative 2a were also evaluated. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)