Fatal misdiagnosis of progressive disseminated histoplasmosis

Disseminated histoplasmosis is the form of a mycosis caused by the fungus Histoplasma capsulatum that mainly occurs in immunosuppressed hosts, usually with non-specific symptoms. In non-endemic areas, where the disease is rarely involved in the differential diagnosis, a delay in treatment may lead t...

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Bibliographic Details
Published inMedical mycology case reports Vol. 45; p. 100662
Main Authors Vasilopoulou, Anthi, Spaho, Marina, Theotokis, Paschalis, Grekou, Alexandra, Meditskou, Soultana, Manthou, Maria Eleni
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.09.2024
Elsevier
Subjects
Arthritis
Differential diagnosis
Disseminated histoplasmosis
Erythema nodosum
Histoplasma capsulatum
Misdiagnosis
Non-endemic area
GI
DH
ESR
Histoplasma capsulatum
Misdiagnosis
EN
CNS
Arthritis
Non-endemic area
PDH
Disseminated histoplasmosis
Differential diagnosis
Erythema nodosum
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Summary:Disseminated histoplasmosis is the form of a mycosis caused by the fungus Histoplasma capsulatum that mainly occurs in immunosuppressed hosts, usually with non-specific symptoms. In non-endemic areas, where the disease is rarely involved in the differential diagnosis, a delay in treatment may lead to severe medical complications. Due to the rising prevalence of disseminated histoplasmosis in these areas, a thorough medical history is regarded as the decisive factor in prompt diagnosis of the disease. We, herein, report the case of an immunocompetent Greek farmer with disseminated histoplasmosis whose condition was initially misdiagnosed, and the consequential inadequate treatment led to his death.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ObjectType-Report-1
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ISSN:2211-7539
2211-7539
DOI:10.1016/j.mmcr.2024.100662