Successful treatment for cryptococcal meningoencephalitis complicated by cerebral salt-wasting syndrome in a patient with chronic lymphocytic leukemia: A clinical case

Cryptococcus neoformans is a common agent of fungal meningoencephalitis in immunocompromised patients. Cerebral salt-wasting syndrome is one of the rare causes of severe hyponatremia in patients with CNS diseases. The paper describes the first clinical case of a patient, whose onset of chronic lymph...

Full description

Saved in:
Bibliographic Details
Published inTerapevtic̆eskii arhiv Vol. 87; no. 11; pp. 99 - 102
Main Authors Potapenko, V G, Konovalenko, I B, Oksema, Е V, Filippova, L N, Dulaeva, E N, Derevyannykh, N А, Krasnoruzhsky, А I, Klimovich, A V, Klimko, N N, Medvedeva, N V
Format Journal Article
LanguageRussian
Published Russia (Federation) "Consilium Medicum" Publishing house 01.01.2015
Subjects
Aged
amphotericin b
Amphotericin B - therapeutic use
Antifungal Agents - therapeutic use
cerebral salt-wasting syndrome
chronic lymphocytic leukemia
Comorbidity
cryptococcus
Fluconazole - therapeutic use
Humans
Hyponatremia - epidemiology
Leukemia, Lymphocytic, Chronic, B-Cell - epidemiology
Male
Meningitis, Cryptococcal - drug therapy
Meningitis, Cryptococcal - epidemiology
meningoencephalitis
Syndrome
Online AccessGet full text

Cover

More Information
Summary:Cryptococcus neoformans is a common agent of fungal meningoencephalitis in immunocompromised patients. Cerebral salt-wasting syndrome is one of the rare causes of severe hyponatremia in patients with CNS diseases. The paper describes the first clinical case of a patient, whose onset of chronic lymphocytic leukemia was complicated by cryptococcal meningoencephalitis presenting with mental disorders and severe electrolytic imbalance. Antifungal treatment with amphotericin B and fluconazole could alleviate an infectious process and metabolic disturbances.
ISSN:0040-3660
2309-5342
DOI:10.17116/terarkh2015871199-102