The versatility of pyrene and its derivatives on sp2 carbon nanomaterials for bioelectrochemical applications

• Published in: Synthetic metals Vol. 292; p. 117219
• Main Authors: Holzinger, Michael, Cosnier, Serge, Buzzetti, Paulo Henrique M.
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.01.2023; Elsevier
• Subjects: Biofuel cells; Biosensors; Carbon nanotubes; Chemical Sciences; Graphene; Pyrene; TPEP; Biofuel cells; bispyrene-ABTS; Carbon nanotubes; AcPyTACN; pyrene-KDDD; pyrene-NHS; CNTs; FAD-GDH; NHS; XPS; SWCNTs; FAD; buckypaper; CODH; DARPins; Pyrene; Graphene; DNA; TEG; PAHs; MWCNTs; Biosensors; TEM; ABTS; pyrenedione-NHS; Pyrene Carbon nanotubes Graphene Biosensors Biofuel cells
• ISSN: 0379-6779; 1879-3290
• DOI: 10.1016/j.synthmet.2022.117219

Pyrene and its derivatives became a standard tool for the immobilization of bioentities on nanostructured sp2 carbon such as graphene and carbon nanotubes (CNTs) for bioelectrochemical applications. Stable π-stacking interaction between these compounds can be formed under mild conditions without affecting sensitive anchor functions of pyrene or introducing defect groups on the carbon material. Pyrene has further beneficial properties for bioelectrochemical studies. Pyrene itself can form supramolecular inclusion complexes with β-cyclodextrin and can even interact with the hydrophobic domain of a laccase enzyme allowing oriented immobilization. Pyrene can further act as cross-linker, be electropolymerized to reinforce the formed layer, and also be electro-oxidized becoming an efficient redox mediator for the electron transfer with a flavin adenine dinucleotide (FAD) co-factor. This versatility of pyrene and its derivatives for bioelectrochemical applications are focused here besides some original anchoring methods for biomolecules. [Display omitted] •Pyrene and derivatives to stable π-stacking interaction with sp2 carbon structures.•Ideal tool for interfacing carbon nanomaterials with biomolecules.•Beneficial properties to reinforce carbon-based material.•Pyrenes can also be electropolymerized to form stable coatings.•Electro-oxidation converts pyrenes into efficient redox mediators.