On the interaction of oxovanadium(IV) with homocysteine

• Published in: Biological trace element research Vol. 105; no. 1-3; pp. 53 - 58
• Main Authors: Ferrer, E G, Williams, P A M, Baran, E J
• Format: Journal Article
• Language: English
• Published: United States Springer Nature B.V 2005
• Subjects: Absorption spectroscopy; Amino acids; Amino Acids - chemistry; Aqueous solutions; Cations; Cysteine - chemistry; Detoxification; Electrons; Homocysteine; Homocysteine - chemistry; Homocysteine - metabolism; Hydrogen-Ion Concentration; Ligands; Metals - chemistry; Models, Chemical; Spectrophotometry; Trace Elements; Vanadates - chemistry; Vanadates - metabolism; Vanadium
• ISSN: 0163-4984; 0163-4984; 1559-0720
• DOI: 10.1385/bter:105:1-3:053

The interaction of the VO2+ cation with homocysteine was investigated by electron absorption spectroscopy in aqueous solution at different metal-to-ligand ratios. The direct reduction of vanadate(V) solutions with homocysteine was also investigated. The results suggest that the interaction is different from that found in the case of cysteine and occurs through pairs of amino and carboxylate groups of the amino acid. The interaction of VO2+ with homocystine, the oxidation product of homocysteine, was also analyzed. The interest of the results in relation to vanadium metabolism and detoxification is briefly discussed.