Line-scanning detection instrument for photonic crystal enhanced fluorescence

• Published in: Optics letters Vol. 37; no. 13; p. 2565
• Main Authors: Chaudhery, Vikram, Lu, Meng, Huang, Cheng-Sheng, Polans, James, Tan, Ruimin, Zangar, Richard C, Cunningham, Brian T
• Format: Journal Article
• Language: English
• Published: United States 01.07.2012
• Subjects: Biomarkers, Tumor - analysis; Nanostructures; Photons; Protein Array Analysis; Spectrometry, Fluorescence - instrumentation; Surface Properties

A laser line-scanning instrument was developed to optimize the near-field enhancement capability of a one-dimensional photonic crystal (PC) for excitation of surface-bound fluorophores. The excitation laser beam is shaped into an 8 μm × 1 mm line that is focused along the direction of the PC grating...