Multisystem inflammatory syndrome in neonates associated with SARS-CoV-2 infection, a different entity?

Multisystemic inflammatory syndrome in children (MIS-C) is a novel disease that is associated with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). MIS-C usually affects children older than 5 years of age and adolescents, with a median of 8-years and an interquartile range of 3 to 11...

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Published inJournal of neonatal-perinatal medicine Vol. 16; no. 1; pp. 169 - 177
Main Authors Gámez-González, L B, Escárcega-Juárez Ana Silvia, A S, Aguilar-Soto, D E, Colmenero Rascón, M, García Espinosa, A C, Yamazaki-Nakashimada, M A
Format Journal Article
LanguageEnglish
Published Netherlands 01.01.2023
Subjects
Adolescent
Child
Child, Preschool
COVID-19 - complications
Humans
Infant, Newborn
Mucocutaneous Lymph Node Syndrome - complications
Mucocutaneous Lymph Node Syndrome - diagnosis
RNA, Viral
SARS-CoV-2
COVID-19 neonate
SARS-CoV2
multisystem inflammatory syndrome in children
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Summary:Multisystemic inflammatory syndrome in children (MIS-C) is a novel disease that is associated with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). MIS-C usually affects children older than 5 years of age and adolescents, with a median of 8-years and an interquartile range of 3 to 11 years. A multisystemic inflammatory disease has been described in neonates and named MIS-N (multisystemic inflammatory syndrome in Neonates). We report three cases of Mexican newborns with MIS-N presenting with multiorgan compromise and a positive anti-SARS-CoV-2 IgG who developed Kawasaki disease (KD)-like cardiac features and discuss the current dilemma regarding diagnosis and treatment in these patients.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1934-5798
1878-4429
DOI:10.3233/NPM-220990