Methods for the synthesis of aza(deaza)xanthines as a basis of biologically active compounds

The review covers methods for the synthesis of aza(deaza)xanthines, i.e., fused pyrrolo-, pyrazolo- and triazolopyrimidine heterocyclic systems, which are common core structures of various biologically active compounds. The extensive range of modern synthetic approaches is organized according to tar...

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Published inRussian chemical reviews Vol. 85; no. 3; pp. 308 - 334
Main Authors Babkov, D A, Geisman, A N, Khandazhinskaya, A L, Novikov, M S
Format Journal Article
LanguageEnglish
Published Turpion Ltd and the Russian Academy of Sciences 01.01.2016
Subjects
Pharmaceuticals
Synthesis
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Summary:The review covers methods for the synthesis of aza(deaza)xanthines, i.e., fused pyrrolo-, pyrazolo- and triazolopyrimidine heterocyclic systems, which are common core structures of various biologically active compounds. The extensive range of modern synthetic approaches is organized according to target structures and starting building blocks. The presented material is intended to benefit broad audience of specialists in the fields of organic, medicinal and pharmaceutical chemistry. The bibliography includes 195 references.
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ISSN:0036-021X
1468-4837
DOI:10.1070/RCR4496