A facile and direct entry to functionalised Neu5Ac2en derivatives from the methyl ketoside of Neu5Ac methyl esters

Acetolysis of some methyl ketosides of N-acetylneuraminic acid (Neu5Ac) methyl esters, in a one-pot reaction, provides a rapid and efficient access to the corresponding 2,3-unsaturated Neu5Ac (Neu5Ac2en) derivatives.

Saved in:
Bibliographic Details
Published inChemical communications (Cambridge, England) no. 17; pp. 2017 - 2018
Main Authors Kok, GB, Groves, DR, vonItzstein, M
Format Journal Article
LanguageEnglish
Published CAMBRIDGE Royal Soc Chemistry 1996
Subjects
Chemistry
Chemistry, Multidisciplinary
Physical Sciences
Science & Technology
BEHAVIOR
STRUCTURAL VARIATIONS
SIALIDASE
RECEPTOR
INFLUENZA-VIRUS
INHIBITOR
N-ACETYLNEURAMINIC ACID
Online AccessGet full text

Cover

More Information
Summary:Acetolysis of some methyl ketosides of N-acetylneuraminic acid (Neu5Ac) methyl esters, in a one-pot reaction, provides a rapid and efficient access to the corresponding 2,3-unsaturated Neu5Ac (Neu5Ac2en) derivatives.
ISSN:1359-7345
1364-548X
DOI:10.1039/cc9960002017