Serum albumin enhances the membrane activity of ZnO nanoparticles
We investigate the effect of serum albumin on the interaction of ZnO nanoparticles with DOPC lipid membranes and show that the size-stabilizing effect of the protein corona enhances their interaction with lipid membranes, which manifests, in part, as an increased ordering in the lipid packing.
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Published in | Chemical communications (Cambridge, England) Vol. 49; no. 39; pp. 4172 - 4174 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
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England
14.05.2013
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Abstract | We investigate the effect of serum albumin on the interaction of ZnO nanoparticles with DOPC lipid membranes and show that the size-stabilizing effect of the protein corona enhances their interaction with lipid membranes, which manifests, in part, as an increased ordering in the lipid packing. |
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AbstractList | We investigate the effect of serum albumin on the interaction of ZnO nanoparticles with DOPC lipid membranes and show that the size-stabilizing effect of the protein corona enhances their interaction with lipid membranes, which manifests, in part, as an increased ordering in the lipid packing. |
Author | Brydson, Rik Milne, Steven J Churchman, Adam H Wallace, Rachel Brown, Andy P Beales, Paul A |
Author_xml | – sequence: 1 givenname: Adam H surname: Churchman fullname: Churchman, Adam H organization: Centre for Molecular Nanoscience, School of Chemistry, University of Leeds, Leeds, LS2 9JT, UK – sequence: 2 givenname: Rachel surname: Wallace fullname: Wallace, Rachel – sequence: 3 givenname: Steven J surname: Milne fullname: Milne, Steven J – sequence: 4 givenname: Andy P surname: Brown fullname: Brown, Andy P – sequence: 5 givenname: Rik surname: Brydson fullname: Brydson, Rik – sequence: 6 givenname: Paul A surname: Beales fullname: Beales, Paul A |
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SubjectTerms | Animals Cattle Cell Membrane - chemistry Cell Membrane - metabolism Humans Lipid Bilayers - chemistry Lipid Bilayers - metabolism MCF-7 Cells Metal Nanoparticles - chemistry Phosphatidylcholines - chemistry Serum Albumin, Bovine - chemistry Serum Albumin, Bovine - metabolism Zinc Oxide - chemistry |
Title | Serum albumin enhances the membrane activity of ZnO nanoparticles |
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