Flexible and Stretchable Electrochemical Sensors for Biological Monitoring

The rise of flexible and stretchable electronics has revolutionized biosensor techniques for probing biological systems. Particularly, flexible and stretchable electrochemical sensors (FSECSs) enable the in situ quantification of numerous biochemical molecules in different biological entities owing...

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Published inAdvanced materials (Weinheim) Vol. 37; no. 31; p. e2305917
Main Authors Zhao, Yi, Jin, Kai‐Qi, Li, Jing‐Du, Sheng, Kai‐Kai, Huang, Wei‐Hua, Liu, Yan‐Ling
Format Journal Article
LanguageEnglish
Published Germany Wiley Subscription Services, Inc 01.08.2025
Subjects
Animals
Biomarkers
Biomarkers - analysis
Biomonitoring
Biosensing Techniques - instrumentation
Biosensing Techniques - methods
Biosensors
Chemical sensors
Electrochemical Techniques - instrumentation
Electrochemical Techniques - methods
Electrodes
Electrolytes
Electrolytic cells
Epidermis
Humans
Metabolites
epidermal analysis
cell monitoring
flexible electronics
electrochemical sensors
biochemical molecules
tissue detection
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Abstract The rise of flexible and stretchable electronics has revolutionized biosensor techniques for probing biological systems. Particularly, flexible and stretchable electrochemical sensors (FSECSs) enable the in situ quantification of numerous biochemical molecules in different biological entities owing to their exceptional sensitivity, fast response, and easy miniaturization. Over the past decade, the fabrication and application of FSECSs have significantly progressed. This review highlights key developments in electrode fabrication and FSECSs functionalization. It delves into the electrochemical sensing of various biomarkers, including metabolites, electrolytes, signaling molecules, and neurotransmitters from biological systems, encompassing the outer epidermis, tissues/organs in vitro and in vivo, and living cells. Finally, considering electrode preparation and biological applications, current challenges and future opportunities for FSECSs are discussed.
AbstractList The rise of flexible and stretchable electronics has revolutionized biosensor techniques for probing biological systems. Particularly, flexible and stretchable electrochemical sensors (FSECSs) enable the in situ quantification of numerous biochemical molecules in different biological entities owing to their exceptional sensitivity, fast response, and easy miniaturization. Over the past decade, the fabrication and application of FSECSs have significantly progressed. This review highlights key developments in electrode fabrication and FSECSs functionalization. It delves into the electrochemical sensing of various biomarkers, including metabolites, electrolytes, signaling molecules, and neurotransmitters from biological systems, encompassing the outer epidermis, tissues/organs in vitro and in vivo, and living cells. Finally, considering electrode preparation and biological applications, current challenges and future opportunities for FSECSs are discussed.The rise of flexible and stretchable electronics has revolutionized biosensor techniques for probing biological systems. Particularly, flexible and stretchable electrochemical sensors (FSECSs) enable the in situ quantification of numerous biochemical molecules in different biological entities owing to their exceptional sensitivity, fast response, and easy miniaturization. Over the past decade, the fabrication and application of FSECSs have significantly progressed. This review highlights key developments in electrode fabrication and FSECSs functionalization. It delves into the electrochemical sensing of various biomarkers, including metabolites, electrolytes, signaling molecules, and neurotransmitters from biological systems, encompassing the outer epidermis, tissues/organs in vitro and in vivo, and living cells. Finally, considering electrode preparation and biological applications, current challenges and future opportunities for FSECSs are discussed.
The rise of flexible and stretchable electronics has revolutionized biosensor techniques for probing biological systems. Particularly, flexible and stretchable electrochemical sensors (FSECSs) enable the in situ quantification of numerous biochemical molecules in different biological entities owing to their exceptional sensitivity, fast response, and easy miniaturization. Over the past decade, the fabrication and application of FSECSs have significantly progressed. This review highlights key developments in electrode fabrication and FSECSs functionalization. It delves into the electrochemical sensing of various biomarkers, including metabolites, electrolytes, signaling molecules, and neurotransmitters from biological systems, encompassing the outer epidermis, tissues/organs in vitro and in vivo, and living cells. Finally, considering electrode preparation and biological applications, current challenges and future opportunities for FSECSs are discussed.
Author Jin, Kai‐Qi
Zhao, Yi
Sheng, Kai‐Kai
Huang, Wei‐Hua
Liu, Yan‐Ling
Li, Jing‐Du
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  surname: Liu
  fullname: Liu, Yan‐Ling
  organization: College of Chemistry and Molecular Sciences Wuhan University Wuhan 430072 China
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ID FETCH-LOGICAL-c323t-934a6531f775cc31f29a78c8dfcad3fbd5d1ec67e835cd2710ee43eedb120d873
ISSN 0935-9648
1521-4095
IngestDate Fri Jul 11 16:58:04 EDT 2025
Fri Aug 08 08:40:48 EDT 2025
Sat Aug 09 01:32:17 EDT 2025
Thu Apr 24 22:59:16 EDT 2025
Thu Aug 14 00:01:14 EDT 2025
IsPeerReviewed true
IsScholarly true
Issue 31
Keywords epidermal analysis
cell monitoring
flexible electronics
electrochemical sensors
biochemical molecules
tissue detection
Language English
License 2023 Wiley‐VCH GmbH.
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PublicationTitle Advanced materials (Weinheim)
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Snippet The rise of flexible and stretchable electronics has revolutionized biosensor techniques for probing biological systems. Particularly, flexible and stretchable...
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SubjectTerms Animals
Biomarkers
Biomarkers - analysis
Biomonitoring
Biosensing Techniques - instrumentation
Biosensing Techniques - methods
Biosensors
Chemical sensors
Electrochemical Techniques - instrumentation
Electrochemical Techniques - methods
Electrodes
Electrolytes
Electrolytic cells
Epidermis
Humans
Metabolites
Title Flexible and Stretchable Electrochemical Sensors for Biological Monitoring
URI https://www.ncbi.nlm.nih.gov/pubmed/37639636
https://www.proquest.com/docview/3237626858
https://www.proquest.com/docview/2858991716
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