Recurrent and metastatic mesoblastic nephroma in infancy

Local recurrence or metastasis of mesoblastic nephroma is extremely uncommon. The first report of a child with mesoblastic nephroma to have both of these problems is presented. The usual course of mesoblastic nephroma is benign, with nephrectomy being curative. Adjuvant treatment is not necessary an...

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Bibliographic Details
Published inJournal of clinical oncology Vol. 2; no. 8; p. 956
Main Authors Steinfeld, A D, Crowley, C A, O'Shea, P A, Tefft, M
Format Journal Article
LanguageEnglish
Published United States 01.08.1984
Subjects
Antineoplastic Agents - therapeutic use
Combined Modality Therapy
Female
Humans
Infant
Infant, Newborn
Kidney Neoplasms - mortality
Kidney Neoplasms - pathology
Kidney Neoplasms - therapy
Lung Neoplasms - secondary
Lymphatic Metastasis
Neoplasm Recurrence, Local
Nephrectomy
Prognosis
Wilms Tumor - mortality
Wilms Tumor - pathology
Wilms Tumor - secondary
Wilms Tumor - therapy
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Summary:Local recurrence or metastasis of mesoblastic nephroma is extremely uncommon. The first report of a child with mesoblastic nephroma to have both of these problems is presented. The usual course of mesoblastic nephroma is benign, with nephrectomy being curative. Adjuvant treatment is not necessary and may be lethal. However, a review of the five patients who developed locally recurrent and/or metastatic tumor indicates that chemotherapy and radiotherapy are of benefit and can produce long-term disease-free survival.
ISSN:0732-183X
DOI:10.1200/JCO.1984.2.8.956