Annelation of furan rings to arenes

Benzofurans have been used in various fields of chemistry and technology due to their unique physical, chemical and biological properties. It is primarily a wide range of biological activities of natural and synthetic benzo[b]furan derivatives and their polyfused analogues (naphthofurans, anthrafura...

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Bibliographic Details
Published inRussian chemical reviews Vol. 85; no. 8; pp. 817 - 835
Main Authors Omelchuk, Olga A., Tikhomirov, Alexander S., Shchekotikhin, Andrey E.
Format Journal Article
LanguageEnglish
Published Turpion Ltd and the Russian Academy of Sciences 01.01.2016
Subjects
Aromatic compounds
Bibliographies
Biological properties
Derivatives
Design analysis
Furans
Synthesis
Trends
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Summary:Benzofurans have been used in various fields of chemistry and technology due to their unique physical, chemical and biological properties. It is primarily a wide range of biological activities of natural and synthetic benzo[b]furan derivatives and their polyfused analogues (naphthofurans, anthrafurans, etc.) that attracts a significant scientific interest in the context of using these heterocycles as privileged scaffolds in drug design. This survey covers those methods for the annelation of a furan ring to arenes that have been developed mostly during the last decade. We also analyze trends in synthetic methods of benzofurans. Some synthetic schemes are highly efficient in the synthesis of polyfunctionalized furan derivatives. The bibliography includes 110 references.
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ISSN:0036-021X
1468-4837
DOI:10.1070/RCR4613