Human and bovine respiratory syncytial virus: immunopathologic mechanisms

Human respiratory syncytial virus (HRSV) is the major respiratory tract pathogen of infants and young children. Bovine respiratory syncytial virus (BRSV) is recognised as an important cause of respiratory tract disease in calves. Both of these viruses and their respective diseases share many similar...

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Bibliographic Details
Published inThe Veterinary quarterly Vol. 13; no. 1; p. 47
Main Author Baker, J C
Format Journal Article
LanguageEnglish
Published England 01.01.1991
Subjects
Animals
Cattle
Cattle Diseases - immunology
Humans
Hypersensitivity
Hypersensitivity, Delayed
Immunity, Cellular
Immunity, Maternally-Acquired
Respiratory Syncytial Viruses - immunology
Respirovirus Infections - immunology
Respirovirus Infections - veterinary
Viral Vaccines - immunology
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Summary:Human respiratory syncytial virus (HRSV) is the major respiratory tract pathogen of infants and young children. Bovine respiratory syncytial virus (BRSV) is recognised as an important cause of respiratory tract disease in calves. Both of these viruses and their respective diseases share many similarities. Immunopathologic mechanisms have been proposed to be involved in the pathogenesis of respiratory syncytial virus (RSV) infections. This review examines the current understanding of the role of immunopathologic mechanisms in RSV infections. The role of vaccines in inducing hypersensitivity is also examined. Additionally, non-immunopathogenic mechanisms involved in RSV infections are discussed.
ISSN:0165-2176
DOI:10.1080/01652176.1991.9694284