Exploring the U-Net++ Model for Automatic Brain Tumor Segmentation

• Published in: IEEE access Vol. 9; pp. 125523 - 125539
• Main Authors: Micallef, Neil, Seychell, Dylan, Bajada, Claude J.
• Format: Journal Article
• Language: English
• Published: Piscataway IEEE 2021; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Adaptation; Adaptation models; Brain; Brain cancer; Brain modeling; Brain tumor; BraTS; Decoding; Deep learning; Image segmentation; Medical imaging; Post-processing; Predictive models; Tumors; U-Net
• ISSN: 2169-3536; 2169-3536
• DOI: 10.1109/ACCESS.2021.3111131

The accessibility and potential of deep learning techniques have increased considerably over the past years. Image segmentation is one of the many fields which have seen novel implementations being developed to solve problems in the domain. U-Net is an example of a popular deep learning model designed specifically for biomedical image segmentation, initially proposed for cell segmentation. We propose a variation of the U-Net++ model, which is itself an adaptation of U-Net, and evaluate its brain tumor segmentation capabilities. The proposed approach obtained Dice Coefficient scores of 0.7192, 0.8712, and 0.7817 for the Enhancing Tumor, Whole Tumor and Tumor Core classes of the BraTS 2019 challenge Validation Dataset. The proposed approach differs from the standard U-Net++ model in a number of ways, including the loss function, number of convolutional blocks, and method of employing deep supervision. Data augmentation and post-processing techniques were also implemented and observed to substantially improve the model predictions. Thus, this article presents a novel adaptation of the U-Net++ architecture, which is both lightweight, and performs comparably with peer-reviewed work evaluated on the same data.