Treatment with iron of patients with heart failure with and without anemia

Iron deficiency is a common cause of anemia in otherwise healthy individuals and plays an important role in the development of anemia within the heart failure patient population. Iron-deficient heart failure patients experience worse symptoms and are less exercise tolerant than those without iron de...

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Bibliographic Details
Published inHeart failure clinics Vol. 6; no. 3; p. 305
Main Authors Jelani, Qurat-ul-ain, Attanasio, Philipp, Katz, Stuart D, Anker, Stefan D
Format Journal Article
LanguageEnglish
Published United States 01.07.2010
Subjects
Anemia, Iron-Deficiency - drug therapy
Anemia, Iron-Deficiency - etiology
Anemia, Iron-Deficiency - physiopathology
Exercise Tolerance
Heart Failure - complications
Heart Failure - drug therapy
Heart Failure - prevention & control
Humans
Infusions, Intravenous
Iron - administration & dosage
Iron - metabolism
Iron - therapeutic use
Quality of Life
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Summary:Iron deficiency is a common cause of anemia in otherwise healthy individuals and plays an important role in the development of anemia within the heart failure patient population. Iron-deficient heart failure patients experience worse symptoms and are less exercise tolerant than those without iron deficiency. These symptoms may occur even before clinical anemia is evident. This article reviews studies of the benefits of the use of intravenous iron to treat iron deficiency in anemic and nonanemic heart failure patients and an overview of the physiology and pathophysiology of iron metabolism in chronic heart failure.
ISSN:1551-7136
DOI:10.1016/j.hfc.2010.02.002