Evaluation of cimaterol for finishing swine including a drug withdrawal period

• Published in: Journal of animal science Vol. 67; no. 1; p. 168
• Main Authors: Walker, W R, Johnson, D D, Brendemuhl, J H, Dalrymple, R H, Combs, G E
• Format: Journal Article
• Language: English
• Published: United States 01.01.1989
• Subjects: Administration, Oral; Adrenergic beta-Agonists - administration & dosage; Adrenergic beta-Agonists - pharmacology; Animal Nutritional Physiological Phenomena; Animals; Body Weight - drug effects; Drug Evaluation - veterinary; Ethanolamines - administration & dosage; Ethanolamines - pharmacology; Female; Male; Swine - growth & development
• ISSN: 0021-8812; 1525-3163
• DOI: 10.2527/jas1989.671168x

One hundred fifty crossbred pigs (55 kg) were allotted by weight, sex and litter to a randomized complete-block design with five dietary treatments, six blocks per treatment and five pigs per pen with sex equalized across treatments. Corn-soybean meal-based diets (.65% lysine) with 0, .25 and .5 mg/kg cimaterol were fed, on an ad libitum basis, to pigs slaughtered at an average pen weight of 104 kg/pig. Drug withdrawal prior to slaughter was 1, 3 and 5 d for pigs fed cimaterol at .25 mg/kg and 1 d for those fed cimaterol at .5 mg/kg of diet. Dietary cimaterol level influenced (quadratic, P less than .01) average daily gain during the first 42 d on test; however, daily feed intake and feed conversion ratio were not affected (P greater than .1). Pigs fed .25 mg/kg cimaterol with a 1-d drug withdrawal had 6.8, 7.7 and 13.5% less 10th rib fat depth and 11.1, 6.1 and 13.3% less P2 fat depth than those subjected to either a 3- or 5-d drug withdrawal or those fed the 0 mg/kg cimaterol diet (control), respectively. Overall, pigs fed cimaterol had 7.9% larger longissimus muscle area and 2.6% more kilograms of muscle than pigs fed the control diet. Cimaterol fed at .5 mg/kg resulted in higher (P less than .05) Warner-Bratzler shear force values and altered the proportion of saturation in some long-chain fatty acids, although the total saturated:unsaturated fat ratio was not affected. Pigs fed no cimaterol had less thaw loss (P less than .05) than did those fed other treatments.