Diurnal variation of the tear osmolarity in normal subjects measured by a new microchip system

To show the diurnal variation of tear osmolarity in normal subjects. Thirty volunteers were recruited. Tear osmolarity was measured with TearLab osmolarity system at 3-hour regular intervals between 8:00 am and 5:00 pm. One-way analysis of variance test was used for statistical analysis. Thirty heal...

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Bibliographic Details
Published inEuropean journal of ophthalmology Vol. 22 Suppl 7; p. S1
Main Authors Oncel, Banu Açikalin, Pinarci, Eylem, Akova, Yonca A
Format Journal Article
LanguageEnglish
Published United States 2012
Subjects
Adolescent
Adult
Circadian Rhythm - physiology
Diagnostic Techniques, Ophthalmological - instrumentation
Humans
Lab-On-A-Chip Devices
Male
Middle Aged
Osmolar Concentration
Reference Values
Tears - chemistry
Young Adult
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Summary:To show the diurnal variation of tear osmolarity in normal subjects. Thirty volunteers were recruited. Tear osmolarity was measured with TearLab osmolarity system at 3-hour regular intervals between 8:00 am and 5:00 pm. One-way analysis of variance test was used for statistical analysis. Thirty healthy volunteers (all men) with a mean age of 29.6 ± 4.3 years (range 18-45) were recruited. The difference between measurements at 8:00 am and 11:00 am, 8:00 am and 2:00 pm, 8:00 am and 5:00 pm, 11:00 am and 2:00 pm, 11:00 am and 5:00 pm, and 2:00 pm and 5:00 pm were not statistically significant (one-way analysis of variance test, p>0.05). In normal subjects, tear osmolarity seems to have a stable profile during the daytime.
ISSN:1724-6016
DOI:10.5301/ejo.5000084