Chromosomal studies on 934 induced abortuses of middle-aged pregnant women

A total of 934 induced abortuses of middle-aged pregnant women (35-48 years old) were chromosomally surveyed. The mean gestational age was 7.6 +/- 2.0 (S.D.) weeks after the first day of the last menstrual period, and the mean maternal age was 39.6 +/- 2.7 (S.D.) years. There was a high incidence of...

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Bibliographic Details
Published inAsia-Oceania journal of obstetrics and gynaecology Vol. 16; no. 3; p. 275
Main Authors Hoshi, N, Yamagami, Y, Hanatani, K, Tanaka, T, Fujimoto, S
Format Journal Article
LanguageEnglish
Published Japan 01.09.1990
Subjects
Abortion, Induced
Adult
Chromosome Aberrations
Female
Humans
Karyotyping
Maternal Age
Middle Aged
Parity
Pregnancy
Sex Factors
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Summary:A total of 934 induced abortuses of middle-aged pregnant women (35-48 years old) were chromosomally surveyed. The mean gestational age was 7.6 +/- 2.0 (S.D.) weeks after the first day of the last menstrual period, and the mean maternal age was 39.6 +/- 2.7 (S.D.) years. There was a high incidence of chromosomally abnormal fetuses in induced abortions, which markedly increased with the advancing age of the women: 9.6% (40/418) for the 35-39-year-old age group, 20.7% (100/484) for the 40-44-year-old age group, and 43.8% (14/32) for the 45-48-year-old age group, averaging 16.5%.
ISSN:0389-2328
DOI:10.1111/j.1447-0756.1990.tb00238.x