Chemotactic response of vascular smooth muscle cells to acetoacetylated low-density lipoprotein

• Published in: Heart and vessels Vol. 4; no. 2; p. 100
• Main Authors: Naito, M, Hayashi, T, Funaki, C, Kuzuya, M, Asai, K, Kuzuya, F
• Format: Journal Article
• Language: English; Japanese
• Published: Japan 01.06.1988
• Subjects: Animals; Arteriosclerosis - pathology; Cattle; Cell Movement; Cells, Cultured; Chemotaxis - drug effects; Lipoproteins, LDL - pharmacology; Muscle, Smooth, Vascular - cytology

We studied the effect of acetoacetylated low-density lipoprotein (LDL), which is recognized by the scavenger receptor, on the migration of fetal bovine aortic smooth muscle cells in culture, using a Neuro Probe 48-well microchemotaxis chamber. Acetoacetylated LDL is chemotactic and chemokinetic for...