Expression of ICAM-1 and HLA-DR by human conjunctival epithelial cultured cells and modulation by nedocromil sodium

• Published in: Journal of ocular pharmacology and therapeutics Vol. 14; no. 6; p. 517
• Main Authors: Diebold, Y, Calonge, M, Carretero, V, Fernández, N, Herreras, J M
• Format: Journal Article
• Language: English
• Published: United States 01.12.1998
• Subjects: Anti-Allergic Agents - pharmacology; Anti-Inflammatory Agents - pharmacology; Cells, Cultured; Conjunctiva - cytology; Conjunctiva - drug effects; Conjunctiva - metabolism; Epithelial Cells - drug effects; Epithelial Cells - metabolism; HLA-DR Antigens - metabolism; Humans; Immunoenzyme Techniques; Intercellular Adhesion Molecule-1 - metabolism; Interferon-gamma - pharmacology; Interleukin-1 - pharmacology; Nedocromil - pharmacology; Recombinant Proteins

It is unclear whether conjunctival epithelial cells participate in the development of immune-mediated events. Using a previously reported in vitro system of human conjunctival epithelium, we determined whether conjunctival epithelial cells express two relevant markers in the antigenic presentation p...