Crescentic Glomerulonephritis in IgA Multiple Myeloma: A Case Report

Background: There are few reports of glomerulonephritis (GN) with crescents and a rapidly progressive course that lead to a diagnosis of a previously unsuspected B-cell dyscrasia. Case Presentation: We report a case of rapidly progressive GN: the patient showed no evidence of etiology at the time of...

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Bibliographic Details
Published inNephron extra Vol. 1; no. 1; pp. 69 - 72
Main Authors Moscoso-Solorzano, Grace T., Madureira-Silva, Marcus V., Balda, Carlos, Franco, Marcello F., Mastroianni-Kirsztajn, Gianna
Format Journal Article
LanguageEnglish
Published Basel, Switzerland S. Karger AG 08.09.2011
Subjects
Case Report
Glomerulonephritis
Rapidly progressive glomerulonephritis
Crescents
B-cell dyscrasia
Multiple myeloma
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Summary:Background: There are few reports of glomerulonephritis (GN) with crescents and a rapidly progressive course that lead to a diagnosis of a previously unsuspected B-cell dyscrasia. Case Presentation: We report a case of rapidly progressive GN: the patient showed no evidence of etiology at the time of biopsy and was diagnosed as IgA multiple myeloma (MM) during investigation based on a renal biopsy. He presented diffuse proliferative and exudative GN and marked plasma cell infiltration of the kidney. Conclusion: The present case raises the possibility that proliferative GN with crescents may be a rare mode of presentation of MM.
ISSN:1664-5529
1664-5529
DOI:10.1159/000331217