Unsuspected Alzheimer disease in a patient with Multiple sclerosis and progressive aphasia

•Cognitive dysfunction is a common feature in MS.•Diagnosing cognitive dysfunction due to an accompanying neurodegenerative dementia represents a challenge.•AD biomarkers may be helpful in selected MS patients with severe, cortical type, cognitive dysfunction.

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Bibliographic Details
Published inMultiple sclerosis and related disorders Vol. 45; p. 102349
Main Authors Borrelli, S., Genoud-Prachex, T., Meyer, M., Démonet, J.-F., Rouaud, O.
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.10.2020
Subjects
18F-FDG PET
Alzheimer disease
Alzheimer Disease - complications
Alzheimer Disease - diagnostic imaging
Aphasia
Brain - diagnostic imaging
Cognitive impairment
Humans
Multiple Sclerosis - complications
Multiple Sclerosis - diagnostic imaging
Multiples sclerosis
Positron-Emission Tomography
Aphasia
Multiples sclerosis
18F-FDG PET
Alzheimer disease
Cognitive impairment
F-FDG PET
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Summary:•Cognitive dysfunction is a common feature in MS.•Diagnosing cognitive dysfunction due to an accompanying neurodegenerative dementia represents a challenge.•AD biomarkers may be helpful in selected MS patients with severe, cortical type, cognitive dysfunction.
ISSN:2211-0348
2211-0356
DOI:10.1016/j.msard.2020.102349