Role of Hypofractionated Stereotactic Radiosurgery in Recurrent Pineal Parenchymal Tumors of Intermediate Differentiation: A Case Report and Review of the Literature

A pineal parenchymal tumor of intermediate differentiation (PPID) is a rare entity, and optimal treatment is still unclear. Combined multimodality treatment should be considered in PPID due to high recurrence rates. Gross total resection is the first choice of treatment, however, it may not be feasi...

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Bibliographic Details
Published inCurēus (Palo Alto, CA) Vol. 12; no. 8
Main Authors Beduk Esen, Caglayan Selenge, Yazici, Gozde, Berker, Mustafa, Zorlu, Faruk
Format Journal Article
LanguageEnglish
Published Palo Alto (CA) Cureus 13.08.2020
Subjects
Neurosurgery
Oncology
Radiation Oncology
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Summary:A pineal parenchymal tumor of intermediate differentiation (PPID) is a rare entity, and optimal treatment is still unclear. Combined multimodality treatment should be considered in PPID due to high recurrence rates. Gross total resection is the first choice of treatment, however, it may not be feasible in every case due to location. Stereotactic radiosurgery (SRS) can be considered for the treatment of primary and recurrent disease, as it enables us to deliver a high radiation dose to the target while minimizing radiation exposure to normal tissue. In this report, we present a case treated with hypofractionated SRS for recurrent/metastatic PPID after the primary tumor was controlled with the combination of surgery and conventionally fractionated radiotherapy.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.9709