Current and Future Approaches for Effective Cancer Imaging and Treatment

Cancer poses a major health problem, not only due to cancer-related deaths but also because of treatment toxicities. This review discusses early diagnosis and strategies to overcome treatment difficulties, to facilitate recovery, and prevent deaths. Generally, noninvasive techniques such as computed...

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Published inCancer biotherapy & radiopharmaceuticals Vol. 33; no. 2; pp. 39 - 51
Main Authors Karpuz, Merve, Silindir-Gunay, Mine, Ozer, Asuman Yekta
Format Journal Article
LanguageEnglish
Published United States Mary Ann Liebert, Inc 01.03.2018
Subjects
Cancer
Cancer therapies
Chemotherapy
Combined treatment
Computed tomography
Diagnosis
Drug delivery
Drug delivery systems
Fatalities
Magnetic resonance imaging
NMR
Nuclear magnetic resonance
Radiation therapy
Single photon emission computed tomography
Surgery
Tomography
Toxicity
Ankara Turkey
Turkey
cancer treatment
cancer diagnosis
theranostics
combination cancer therapy
nanosized drug delivery systems
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Summary:Cancer poses a major health problem, not only due to cancer-related deaths but also because of treatment toxicities. This review discusses early diagnosis and strategies to overcome treatment difficulties, to facilitate recovery, and prevent deaths. Generally, noninvasive techniques such as computed tomography (CT), magnetic resonance imaging (MRI), single photon emission computed tomography (SPECT) and positron emission computed tomography (PET), and their hybrid systems, including SPECT/CT, PET/CT, and PET/MRI, are used in diagnosis of cancer. Cancer treatment in clinics still comprises conventional methods such as chemotherapy, radiotherapy, and surgery. However, these techniques and methods are often inadequate. Therefore, new approaches, including the formulation of actively and/or passively targeted nanosized drug delivery systems and combined treatment protocols, are being investigated. In this article, conventional cancer imaging and treatment are reviewed. In addition, the formulation of nanosized systems and their use in cancer treatment are discussed and combined diagnostic and therapeutic (theranostic) approach are proposed as additional cancer therapies.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1084-9785
1557-8852
DOI:10.1089/cbr.2017.2378