In-vitro corrosion and biocompatibility properties of heat treated Mg-4Y-2.25Nd-0.5Zr alloy

• Published in: Materials chemistry and physics Vol. 304; p. 127873
• Main Authors: Jana, Anuradha, Balla, Vamsi Krishna, Das, Mitun
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.08.2023
• Subjects: Biocompatibility; Biomaterial; Corrosion; Mg-4Y-2.25Nd-0.5Zr alloy; Powder metallurgy; Biocompatibility; Mg-4Y-2.25Nd-0.5Zr alloy; Biomaterial; Corrosion; Powder metallurgy
• ISSN: 0254-0584; 1879-3312
• DOI: 10.1016/j.matchemphys.2023.127873

In this study, corrosion and biocompatibility behaviour of Mg-4Y-2.25Nd-0.5Zr alloy (Mg-Y-Nd-Zr) was investigated. The pre-alloyed powder of Mg-Y-Nd-Zr was processed using powder metallurgy (PM) method, followed by further heat treatment at 250 °C for 12 h. The microstructural features of as-sintered and heat treated Mg-Y-Nd-Zr alloy showed secondary phases like Mg24Y5 and Mg41Nd5 in α-Mg matrix. In heat treated samples, the alloy showed improved compressive strength and hardness. The hardness and compressive strength was better for the heat treated Mg-Y-Nd-Zr alloy samples (54 ± 2 HV and 243 ± 30 MPa) compared to heat treated pure Mg samples (44 ± 5 HV and 129 ± 11 MPa). This is because of rearrangement of the secondary phases in the matrix. The corrosion current density of Mg-Y-Nd-Zr alloy samples reduced by 45% (82.2 μA/cm2 for heat treated and 149.3 μA/cm2 for as-sintered) after heat treatment indicating its better corrosion resistance than as-sintered samples. Both heat treated and as-sintered alloy exhibited good biocompatibility and therefore the Mg-Y-Nd-Zr alloy is a potential candidate for biodegradable implants. •Near net shape manufacturing of Mg-4Y-2.25Nd-0.5Zr alloy and subsequent heat treatment.•Secondary phases like Mg24Y5 and Mg41Nd5 observed in the Mg alloy.•The hardness and compressive strength of the alloy improved after heat treatment.•In vitro cell culture showed cytocompatibility of Mg-Y-Nd-Zr alloy.