Nanomaterials for wound healing: Current status and futuristic frontier

• Published in: Biomedical Technology Vol. 6; pp. 26 - 45
• Main Authors: Nandhini, J., Karthikeyan, E., Rajeshkumar, S.
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.06.2024; KeAi Communications Co., Ltd
• Subjects: Future prospects; Nanomaterials; Organic and inorganic nanomaterials; Toxicity; Wound healing; Nanomaterials; Organic and inorganic nanomaterials; Wound healing; Future prospects; Toxicity
• ISSN: 2949-723X; 2949-723X
• DOI: 10.1016/j.bmt.2023.10.001

Wound healing is a complex process that involves a variety of physical, chemical, and biological processes. Because of their remarkable characteristics and capabilities, nanomaterials have recently emerged as potential therapeutic agents for wound healing. Many different nanomaterial-based wound-healing treatments have been created and put into widespread use. In this review, we compile the most recent research on cutting-edge nanomaterials for wound healing, including both organic and inorganic nanomaterials. We highlight prospective approaches for developing nanomaterial-based wound healing therapy procedures and talk about the benefits and limitations of these treatments. Future prospects for wound healing therapies based on nanomaterials are discussed, including the need to address toxicity concerns, the scalability of production, and the long-term stability of nanomaterials. The safety and effectiveness of nanomaterials depend on further investigation into their design, interactions with biological systems, and the results of rigorous preclinical and clinical trials. There is great potential for a dramatic improvement in patient outcomes with the introduction of nanomaterial-based wound healing therapies. [Display omitted] •Nanomaterials have shown promising results in wound healing due to their unique properties such as high surface area to volume ratio and tunable surface chemistry.•Various types of nanomaterials, including nanoparticles, nanofibers, and nanocomposites, have been extensively studied for their potential applications in wound healing.•Nanomaterials can accelerate wound healing by promoting cell migration, proliferation, and differentiation, as well as modulating the inflammatory response and promoting angiogenesis.•However, there are still challenges that need to be addressed before nanomaterials can be widely adopted in clinical practice, such as biocompatibility, long-term safety, and regulatory considerations.•In the future, advancements in nanotechnology and the development of personalised medicine may overcome these challenges and pave the way for widespread use of nanomaterials in wound healing. By tailoring nanomaterials to each individual's specific needs, healthcare professionals can ensure optimal healing outcomes while minimising the risk of adverse effects