Plasmonic nanohalo optical probes for highly sensitive imaging of survivin mRNA in living cells

A strategy is designed for sensitive detection of tumor biomarker survivin mRNA based on resonance Rayleigh scattering of a single AuNP nanohalo probe that couples large gold nanoparticles (L-AuNPs, 52 nm) with small AuNPs (S-AuNPs, 18 nm) through the affinity interaction between streptavidin and bi...

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Published inChemical communications (Cambridge, England) Vol. 52; no. 74; pp. 11052 - 11055
Main Authors Qian, Guang-Sheng, Kang, Bin, Zhang, Zhuo-Lei, Li, Xiang-Ling, Zhao, Wei, Xu, Jing-Juan, Chen, Hong-Yuan
Format Journal Article
LanguageEnglish
Published England 25.09.2016
Subjects
Cells (biology)
Gold
Imaging
Nanoparticles
Nanostructure
Plasmonics
Rayleigh scattering
Strategy
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Summary:A strategy is designed for sensitive detection of tumor biomarker survivin mRNA based on resonance Rayleigh scattering of a single AuNP nanohalo probe that couples large gold nanoparticles (L-AuNPs, 52 nm) with small AuNPs (S-AuNPs, 18 nm) through the affinity interaction between streptavidin and biotin. This core-satellite plasmon ruler is further applied to imaging survivin mRNA in living cells.
Bibliography:ObjectType-Article-1
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ISSN:1359-7345
1364-548X
DOI:10.1039/c6cc02831d