Desymmetrization of aziridine with malononitrile using cinchona alkaloid amide/zinc(II) catalysts
The catalytic enantioselective desymmetrization of aziridines with malononitrile has been developed. Good yield and enantioselectivity were obtained by using cinchona alkaloid amide/Zn(II) catalysts. The obtained product can be converted to beta-aminoester, beta-aminoamide and triamide compounds.
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Published in | Chemical communications (Cambridge, England) Vol. 53; no. 11; pp. 1817 - 1820 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
CAMBRIDGE
Royal Soc Chemistry
02.02.2017
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Subjects | |
Online Access | Get full text |
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Summary: | The catalytic enantioselective desymmetrization of aziridines with malononitrile has been developed. Good yield and enantioselectivity were obtained by using cinchona alkaloid amide/Zn(II) catalysts. The obtained product can be converted to beta-aminoester, beta-aminoamide and triamide compounds. |
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Bibliography: | KAKEN ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1359-7345 1364-548X |
DOI: | 10.1039/c6cc09457k |