Label-free colorimetric assay for DNA methylation based on unmodified Au nanorods as a signal sensing probe coupled with enzyme-linkage reactions

Using unmodified Au nanorods with enzyme-linkage reaction, a label-free colorimetric method for simple and convenient assay of DNA methylation is presented.

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Bibliographic Details
Published inChemical communications (Cambridge, England) Vol. 49; no. 34; pp. 3546 - 3548
Main Authors Zheng, Xiang-Juan, Qiu, Jian-Ding, Zhang, Li, Wang, Zhong-Xia, Liang, Ru-Ping
Format Journal Article
LanguageEnglish
Published England 04.05.2013
Subjects
Cetrimonium Compounds - chemistry
Chemical communication
Colorimetry - methods
Deoxyribonucleases, Type II Site-Specific - chemistry
DNA - chemistry
DNA Methylation
Gold - chemistry
Nanotubes - chemistry
Site-Specific DNA-Methyltransferase (Adenine-Specific) - chemistry
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Summary:Using unmodified Au nanorods with enzyme-linkage reaction, a label-free colorimetric method for simple and convenient assay of DNA methylation is presented.
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ISSN:1359-7345
1364-548X
DOI:10.1039/c3cc41486h