A synthesis of homosafranic acid and related compounds
A four step sequence was found to convert 2,2,6-trimethylcyclohexanone, 1 , to 1-(2-hydroxyethyl)-2,6,6-trimethyl-1,3-cyclohexadiene, 2 a (overall yield 76%). An efficient route to homosafranic acid 3 is also described (overall yield 80% from ketone 1 ).
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| Published in | Canadian journal of chemistry Vol. 54; no. 14; pp. 2310 - 2313 |
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| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
Ottawa, Canada
NRC Research Press
15.07.1976
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| Online Access | Get full text |
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| Summary: | A four step sequence was found to convert 2,2,6-trimethylcyclohexanone,
1
, to 1-(2-hydroxyethyl)-2,6,6-trimethyl-1,3-cyclohexadiene,
2
a (overall yield 76%). An efficient route to homosafranic acid
3
is also described (overall yield 80% from ketone
1
). |
|---|---|
| ISSN: | 0008-4042 1480-3291 |
| DOI: | 10.1139/v76-328 |