Advances in the research of plant-derived natural products against retinoblastoma

Retinoblastoma (RB) is a highly aggressive ocular tumor, and due to socioeconomic and medical constraints, many children receive treatment only in the metaphase and advanced clinical stages, resulting in high rates of blindness and disability. Although several approaches exist in the treatment of RB...

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Bibliographic Details
Published inInternational journal of ophthalmology Vol. 15; no. 8; pp. 1391 - 1400
Main Authors Liu, Jing-Chen, Dong, Kai-Ye, Li, Ming-Jun, Sun, Shu-Guang, Li, Cai-Rui
Format Journal Article
LanguageEnglish
Published International Journal of Ophthalmology Press 18.08.2022
Press of International Journal of Ophthalmology (IJO PRESS)
Subjects
apoptosis
cell cycle
drug resistance
plant-derived
retinoblastoma
Review
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Summary:Retinoblastoma (RB) is a highly aggressive ocular tumor, and due to socioeconomic and medical constraints, many children receive treatment only in the metaphase and advanced clinical stages, resulting in high rates of blindness and disability. Although several approaches exist in the treatment of RB, some children with the disease do not have satisfactory results because of various factors. Plant-derived natural products have shown definite therapeutic effects in the treatment of various tumors and are also widely used in the study of RB. We review plant-derived natural products used in the study of anti-RB to provide ideas for the clinical application of these drugs and the development of new therapeutic drugs.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Co-first authors: Jing-Chen Liu, Chun-Li Zhang, and Kai-Ye Dong
ISSN:2222-3959
2227-4898
DOI:10.18240/ijo.2022.08.24