South asian patients with ischemic stroke : Intracranial large arteries are the predominant site of disease

• Published in: Stroke (1970) Vol. 38; no. 9; pp. 2592 - 2594
• Main Authors: DE SILVA, Deidre A, WOON, Fung-Peng, LEE, Moi-Pin, CHEN, Christopher P. L. H, CHANG, Hui-Meng, WONG, Meng-Cheong
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 01.09.2007
• Subjects: Arteries - pathology; Asia, Southeastern; Biological and medical sciences; Blood. Blood coagulation. Reticuloendothelial system; Brain Ischemia - pathology; Cerebrovascular Circulation; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy; Humans; Male; Medical sciences; Middle Aged; Nervous system (semeiology, syndromes); Neurology; Pharmacology. Drug treatments; Prospective Studies; Regression Analysis; Retrospective Studies; Stroke - pathology; Vascular Diseases - pathology; Vascular diseases and vascular malformations of the nervous system; Asia, Southeastern; Human; Hypertension; Intracranial; Cerebral infarction; Stroke; Nervous system diseases; South; Cardiovascular disease; Inflammation; South Asian; Cerebral disorder; Vascular disease; Central nervous system disease; Brain ischemia; Cerebrovascular disease; ischemic stroke
• ISSN: 0039-2499; 1524-4628
• DOI: 10.1161/STROKEAHA.107.484584

South Asians are the most prevalent ethnic group in the world. Intracranial disease is the most common vascular lesion worldwide. We prospectively studied 200 consecutive ethnic South Asian patients with acute ischemic stroke in Singapore. Intracranial large-artery disease was prevalent among 54% of all stroke subtypes and was independently associated with hypertension and higher serum erythrocyte sedimentation rate. Among ethnic South Asian patients with ischemic stroke, intracranial large arteries are the predominant site of disease.