Value of ctDNA methylation biomarkers in diagnosis of colorectal tumors

DNA methylation alterations have been identified as promising biological markers for early-stage colorectal cancer detection. Here, the authors highlight some recent advances in DNA methylation and its role in the early diagnosis and overall disease course management of colorectal tumors. New insigh...

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Published inEpigenomics Vol. 15; no. 18; pp. 891 - 893
Main Authors Shi, Yun-Jie, Dong, Yuan-Hang, Mei, Zu-Bing, Wang, Hao
Format Journal Article
LanguageEnglish
Published Future Medicine Ltd 01.09.2023
Subjects
advanced adenomas
biomarkers
circulating tumor DNA
colorectal cancer
CpG islands
ctDNA
DNA methylation
early-stage diagnosis
epigenetics
liquid biopsy
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Summary:DNA methylation alterations have been identified as promising biological markers for early-stage colorectal cancer detection. Here, the authors highlight some recent advances in DNA methylation and its role in the early diagnosis and overall disease course management of colorectal tumors. New insights into DNA methylation biomarkers for colorectal cancer early diagnosis and management are discussed.
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ISSN:1750-1911
1750-192X
DOI:10.2217/epi-2023-0227