Aqueous one-pot synthesis of bright and ultrasmall CdTe/CdS near-infrared-emitting quantum dots and their application for tumor targeting in vivo

CdTe/CdS core(small)/shell(thick) quantum dots (QDs) with tunable near-infrared fluorescence were directly synthesized in aqueous phase through a facile one-step strategy. The QDs possessed bright fluorescence, ultrasmall size, excellent photostability and good biocompatibility. Their applicability...

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Published inChemical communications (Cambridge, England) Vol. 48; no. 41; pp. 4971 - 4973
Main Authors Chen, Li-Na, Wang, Jing, Li, Wen-Tao, Han, He-You
Format Journal Article
LanguageEnglish
Published England 21.05.2012
Subjects
Animals
biocompatibility
bioimaging
Cadmium Compounds - chemical synthesis
Cadmium Compounds - chemistry
cadmium sulfide
chemical communication
chemical reactions
fluorescence
Fluorescent Dyes - analysis
Fluorescent Dyes - chemical synthesis
Fluorescent Dyes - chemistry
Mice
Mice, Nude
neoplasms
Neoplasms - diagnosis
photostability
Quantum Dots
Sulfides - chemical synthesis
Sulfides - chemistry
synthesis
Tellurium - chemistry
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ISSN1359-7345
1364-548X
1364-548X
DOI10.1039/c2cc31259j

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Summary:CdTe/CdS core(small)/shell(thick) quantum dots (QDs) with tunable near-infrared fluorescence were directly synthesized in aqueous phase through a facile one-step strategy. The QDs possessed bright fluorescence, ultrasmall size, excellent photostability and good biocompatibility. Their applicability for biological imaging was demonstrated with the in vivo active tumor targeting of nude mice.
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ISSN:1359-7345
1364-548X
1364-548X
DOI:10.1039/c2cc31259j