Single Dose of Doxycycline for the Prevention of Tick-borne Relapsing Fever

Abstract The current postexposure prophylaxis regimen for tick-borne relapsing fever (TBRF) consists of 5 days’ doxycycline. In this observational study of 77 spelunkers at high risk for TBRF, a single dose of 100 mg doxycycline taken up to 72 hours after exposure to ticks was 100% effective in prev...

Full description

Saved in:
Bibliographic Details
Published inClinical infectious diseases Vol. 71; no. 7; pp. 1768 - 1771
Main Authors Binenbaum, Yoav, Ben-Ami, Ronen, Baneth, Gad, Langford, Boaz, Negev, Yoav, Friedlander, Edwa, Shasha, David, Tau, Luba, Paran, Yael
Format Journal Article
LanguageEnglish
Published US Oxford University Press 23.10.2020
Subjects
Animals
Doxycycline - therapeutic use
Humans
Post-Exposure Prophylaxis
Relapsing Fever - prevention & control
Ticks
Online AccessGet full text

Cover

More Information
Summary:Abstract The current postexposure prophylaxis regimen for tick-borne relapsing fever (TBRF) consists of 5 days’ doxycycline. In this observational study of 77 spelunkers at high risk for TBRF, a single dose of 100 mg doxycycline taken up to 72 hours after exposure to ticks was 100% effective in preventing the disease.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Undefined-1
ObjectType-Feature-3
content type line 23
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciaa034