Mycobacterium brisbanense lung infection facilitated by steroid induced adrenal insufficiency

• Published in: APMIS : acta pathologica, microbiologica et immunologica Scandinavica Vol. 127; no. 2; pp. 106 - 108
• Main Authors: Gynthersen, Rosa, Qvist, Tavs, Andersen, Åse B., Katzenstein, Terese L.
• Format: Journal Article
• Language: English
• Published: Denmark Wiley Subscription Services, Inc 01.02.2019
• Subjects: Adrenal glands; Adrenal insufficiency; Adrenal Insufficiency - pathology; Adult; Amikacin - therapeutic use; Anti-Bacterial Agents - therapeutic use; Asthma; Case reports; Clarithromycin - therapeutic use; Drug Therapy, Combination; Humans; Infections; Inhalation; Itraconazole; Lungs; Male; Moxifloxacin - therapeutic use; Mycobacterium; Mycobacterium brisbanense; Mycobacterium Infections, Nontuberculous - drug therapy; Mycobacterium Infections, Nontuberculous - microbiology; nontuberculous mycobacteria; Nontuberculous Mycobacteria - isolation & purification; pulmonary infection; Recurrent infection; Respiration; Respiratory Tract Infections - drug therapy; Respiratory Tract Infections - microbiology; Sputum - microbiology; Steroid hormones; Steroids; nontuberculous mycobacteria; pulmonary infection; Mycobacterium brisbanense; Adrenal insufficiency
• ISSN: 0903-4641; 1600-0463
• DOI: 10.1111/apm.12911

Mycobacterium brisbanense is rapid‐growing nontuberculous mycobacteria. It was first described in 2004 as a human pathogen and only one case report has previously been published. We report a case of M. brisbanense infection in a young man with asthma, recurrent lung infections and secondary adrenal insufficiency induced by inhalation steroids and itraconazole use. The mycobacterial infection was successfully treated with a long‐term multidrug regimen.