Early seizure detection in childhood focal epilepsy with electroencephalogram feature fusion on deep autoencoder learning and channel correlations

• Published in: Multidimensional systems and signal processing Vol. 33; no. 4; pp. 1273 - 1293
• Main Authors: Jiang, Tiejia, Zhu, Jiahua, Hu, Dinghan, Gao, Weidong, Gao, Feng, Cao, Jiuwen
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.12.2022; Springer Nature B.V
• Subjects: Algorithms; Artificial Intelligence; Circuits and Systems; Convulsions & seizures; Cross correlation; Electrical Engineering; Electroencephalography; Engineering; Epilepsy; Feature extraction; Frequencies; Machine learning; Seizures; Signal,Image and Speech Processing; Dimensionality reduction; Early seizure detection; Epileptic state classification; Convolution autoencoder; Focal onset; Spectrum analysis
• ISSN: 0923-6082; 1573-0824
• DOI: 10.1007/s11045-022-00839-7

Recognition of epileptic electroencephalogram (EEG) signals is vital to epileptic seizure detection. Current research on seizure detection mostly focused on generalized seizure analysis. Compared with generalized seizures, childhood focal epilepsy generally originates in one hemisphere of the brain, and the seizure onset patterns vary from patient to patient, making it difficult for analysis. Meanwhile, the frequency, amplitude and rhythm of EEG activities in children of different ages are different, making childhood focal epilepsy detection challenging. In this paper, the channel correlation features (CCF) containing the regional scalp EEG cross correlations and auto-correlations are proposed for children focal epilepsy EEG representation. The spectrum features are also extracted to characterize EEGs in different frequency bands. Further, a convolutional autoencoder (CAE)-based deep feature learning and dimensionality reduction model is proposed for discriminative EEG frequency domain feature extraction. An early seizure detection framework for the childhood focal epilepsy based on the fused CAE and CCF EEG features is finally developed, and an ensemble classification model (ECM) is applied to solve the imbalance issue between ictal, interictal, and preictal. The performance is evaluated on the EEG dataset collected by the Children’s Hospital, Zhejiang University School of Medicine (CHZU). Experiments show that the proposed algorithm can reach to the highest accuracy of 93.57% for the early seizure detection in childhood focal epilepsy.