Bioactive Peptides from Sesame Meal for Broiler Chickens: Its Influence on the Serum Biochemical Metabolites, Immunity Responses and Nutrient Digestibility

• Published in: International journal of peptide research and therapeutics Vol. 27; no. 2; pp. 1297 - 1303
• Main Authors: Salavati, Mohammad Ebrahim, Rezaeipour, Vahid, Abdullahpour, Rohullah, Mousavi, Seyed Naser
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.06.2021; Springer Nature B.V
• Subjects: Animal Anatomy; Aspartate aminotransferase; Biochemistry; Biomedical and Life Sciences; Blood levels; Body weight gain; Cholesterol; Diet; Dietary supplements; Digestibility; Enzymatic activity; Food conversion; Histidine; Histology; Immune response; Immunoglobulin G; Immunoglobulin M; Life Sciences; Low density lipoprotein; Mannan; Metabolites; Methionine; Molecular Medicine; Morphology; Oligosaccharides; Peptides; Pharmaceutical Sciences/Technology; Pharmacology/Toxicology; Physical growth; Polymer Sciences; Poultry; Threonine; Tyrosine; Broilers; Sesame meal; Peptide; Immunity
• ISSN: 1573-3149; 1573-3904
• DOI: 10.1007/s10989-021-10168-1

This study was conducted to evaluate and compare the effects of bioactive peptides derived from sesame meal (BPSM), avilamycin as an antibiotic and mannan-oligosaccharides (MOS) as a prebiotic supplementation on the some serum metabolites, immune response, and ileal nutrient digestibility of broiler chickens. A total of 300 broiler chickens were randomly placed in 6 treatments with 5 replicates of 10 birds each, for 32 days. The experimental treatments consisted of a basal corn-soybean meal or control diet, control diet + 10 mg/kg avilamycin, control diet + 2 gr/kg MOS, control diet + 50, 100 and 150 mg/kg BPSM. According to the results, dietary treatments had no effects on the serum concentration of IgG and IgM (immunity indices), cholesterol, triglyceride, low density lipoprotein (LDL) and enzyme activity of aspartate aminotransferase (AST) as an index for liver health ( P  > 0.05). While the blood concentration of albumin increased in broiler chickens fed diet containing 100 mg/kg BPSM ( P  < 0.05).In nutrient digestibility, addition of 100 mg/kg of BPSM and MOS increased the ileal digestibility coefficients of crude protein and ether extract in broiler chickens ( P  < 0.05). Likewise, ileal digestibility of vital amino acids including histidine, methionine, and tyrosine improved in broiler chickens, which received 100 mg/kg BPSM diet, while threonine digestibility increased in broilers fed MOS diet ( P  < 0.05). Body weight gain and food conversion ratio improved ( P  < 0.05) in the birds received MOS and 100 mg/kg BPSM, respectively. Considering the results of this study, it is concluded that BPSM can be used as a diet supplement in broiler chickens with no negative effect on the immune response and nutrient digestibility.