Biphasic Calcium Phosphate Versus Demineralized Freeze-Dried Bone Allograft in the Treatment of Periodontal Disease: A Clinical and Radiographical Evaluation

• Published in: Curēus (Palo Alto, CA) Vol. 14; no. 9; p. e29131
• Main Authors: Kumar, Santosh, Desai, Nahid, Joshi, Surabhi, Hirani, Tanvi, Gajjar, Shreya, Patel, Chandni, Bhakkand, Sushmita R, Girdhar, Gaurav A, Govindool, Sharaschandra R, Wan Ahmad Fakuradzi, Wan Farizatul Shima, Haque, Mainul
• Format: Journal Article
• Language: English
• Published: Palo Alto Cureus Inc 13.09.2022; Cureus
• Subjects: Calcium phosphates; Dental plaque; Dentistry; Disease; Gum disease; Oral hygiene; Patients; Proteins; Radiology; Skin & tissue grafts; Teeth; Transplantation; India
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.29131

AimThe study aimed to clinically and radiographically evaluate the effect of biphasic calcium phosphate (BCP) versus demineralized freeze-dried bone allograft (DFDBA) in treating periodontal disease.MethodThe study consisted of 44 patients. The sites were randomly assigned to receive one of two treatment modalities (BCP at site 1 and demineralized freeze-dried bone at site 2) by a computerized method. All the clinical data were measured with the help of a University of North Carolina-15 (UNC-15) probe at the baseline, three months, and six months postoperatively. Radiovisiographs were taken using a Rinn XCP® (Dentsply/Rinn Corp, Elgin, IL) system and an oral grid using the paralleling technique. A manual calculation of the defect area was undertaken at the end of six months and was compared with the other groups.ResultThe linear bone growth recorded for site 1 at the end of six months was 3.8 ± 1.14 mm, and site 2 was 4.6 ± 1.07 mm. The intergroup comparison showed more remarkable linear bone growth in site 2, which was statistically insignificant, with a mean difference of 0.8 ± 1.23 mm and a p-value of 0.07.ConclusionImprovements were observed on all the documented parameters. However, the sites treated with DFDBA showed better periodontal regeneration.